基本信息
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Bio
I am a biologist and I got my Biology degree at Universitat de Barcelona (UB). I obtained my PhD in 2004 in the laboratory of Research in Genetics and Molecular Biology of Mitochondrial Proteins and Associated Diseases, of the Biochemistry and Molecular Biology department of the UB. My PhD thesis was directed by Francesc Villaroya and Dr. Marta Giralt and was about the study of the effects of the antiretroviral drugs against HIV-1 on brown adipose tissue, adipocyte differentiation and the factors that control the mitochondrial biogenesis. During my PhD I got the opportunity of learning many cellular and molecular biology techniques as well
as acquire the necessary skills to work in a lab in autonomously and efficiently way.
In 2005 I started working in the Cell Signaling Research group, directed by Dr. Francesc Posas at the Health and Experimental Sciences Department in Universitat Pompeu Fabra (UPF). During five years I worked as a lab manager, organizing the bacterial and yeast collections of the group, coordinating the technical staff, taking care of the informatics material as well as doing tasks related with occupational risk prevention management, especially of the radioactive facility. Besides my work as a lab manager, I participated in many research projects that allowed me to learn new and different laboratory techniques and extend my knowledge in the cell signaling field. These studies lead to the publication of some scientific papers.
In 2012 I started working at the IrsiCaixa AIDS Research Institute in the Virology and Cellular Immunology (VIC) group, directed by Dr. Julià Blanco. The main objective of the group was the study of the HIV envelope proteins. First, we dedicated good part of our efforts to study the humoral response against the viral envelope, with the development of new assays to identify protective and non-protective responses and the optimization of technologies to isolate and produce monoclonal antibodies. We have also developed two VLP and proteoliposomes 2 platforms for the production of vaccines against HIV, destined to the generation of protective antibodies.
In 2020, I joined the Immunology Group (IgG) a new IrsiCaixa research group led by Dr. Jorge Carrillo. The group’s main research line is the characterization of the immune response to infectious diseases (mainly, but not exclusively, HIV), cancer and autoimmunity. It is currently working on characterization of the humoral respnse to HIV and SARS-CoV-2, with special emphasis on identifying neutralizing antibodies and studying viral spread, and on the development of vaccines against challenging pathogens (such as HIV, Treponema and SARSCoV-2), therapeutic antibodies and new diagnostic tools.
In the groups at IrsiCaixa, I develop support tasks in the research of the different ongoing projects. I perform many basic cellular and molecular biology techniques, cell culture techniques, flow citometry and ELISA (Enzyme-Linked ImmunoSorbent Assay) assays and HIV specific techniques, as neutralization or ADCC (Antibody-Dependent Cell-mediated Citotoxicity) assays. In the field of the immunology associated with HIV I have actively participated with Dr. Jorge Carrillo in the development of a technique that allows the isolation, production and characterization of monoclonal antibodies from human and murine B cells.
Research Interests
Papers共 39 篇Author StatisticsCo-AuthorSimilar Experts
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Research Square (Research Square)no. 1 (2024): 1-18
npj Vaccinesno. 1 (2024): 1-12
Nature Communicationsno. 1 (2024): 1-18
FRONTIERS IN IMMUNOLOGY (2023): 1291972-1291972
Roser Tachó-Piñot,Habib Bashour,Martyna Filipska,Sonia Tejedor Vaquero,Leire de Campos-Mata, Alba Sáez-Gordón,Júlia Perera-Bel,Mauricio Guzmán, Xavi Marcos-Fa,Pablo Canales-Herrerías, Jorge Domínguez-Barragán, Berta Arcós-Ribas,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
npj Vaccinesno. 1 (2023): 1-13
Research Square (Research Square) (2022)
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