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Another seminal study led to the discovery that blood flow and glucose utilization change more than oxygen consumption in the active brain causing tissue oxygen to vary with brain activity. Finally seeking to explain task-induced activity decreases in functional brain images, Raichle’s team employed an innovative strategy to define a physiological baseline. This led to the concept of a default mode of brain function and invigorated studies of intrinsic functional activity, an issue largely dormant for more than a century. An important facet of this work was the discovery of a unique fronto-parietal network in the brain that has come to be known as the default network. This network is now the focus of work on brain function in health and disease worldwide.
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bioRxiv : the preprint server for biology (2024)
Proceedings of the National Academy of Sciences of the United States of Americano. 21 (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
Joshua S Siegel,Subha Subramanian, Demetrius A Perry,Benjamin P Kay,Evan M Gordon,Timothy O Laumann,Ravi V Chacko, Travis R Reneau,Nicholas V Metcalf, Christine Horan,Julie A Schweiger,Dean Wong,
medRxiv : the preprint server for health sciences (2023)
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C. Carroll,M. Stanley, R. Irmen,A. Mitra, J. Snipes,M. Raichle,D. Holtzman, R. Gould,K. Kishida,S. Macauley
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biorxiv(2022)
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