基本信息
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Career Trajectory
Bio
Marc Poirot is first class research director (DR1) at the Institut National de la Santé et de la Recherche Médicale (INSERM). He heads the team ‘Sterol metabolism and therapeutic innovations in oncology’ (Toulouse, France) at the Cancer Research Center of Toulouse”. He received a PhD in Chemical Biology (1991) from the University of Toulouse (France). He did a post-doc at Sanofi in 1991 before becoming tenured at INSERM. He was visiting scientist from 1993 to 1996 in the laboratory of Dr Stoney S. Simons Jr (NIDDK/NIH, Bethesda, USA) to study steroid hormone receptors. Since then, his research has focused on the identification of off-targets of the anti-tumor drug tamoxifen, which led to the definition of the importance of cholesterol metabolism in the pharmacology of antiestrogens. He studies cholesterol metabolism deregulations in cancers and discovered with his team in 2013 Dendrogenin A: a new metabolite with tumor suppressor properties. Dendrogenin A is the first steroidal alkaloid found to date in mammals, revealing the existence of a metabolic pathway at the crossroad of cholesterol and histamine metabolism. He trained tens of postgraduate students, filed a dozen of patent applications, published numerous SCI journal papers, edited/reviewed for many academic journals, served as an evaluation expert for organizations such as the French National Research Agency. He is co-founder of the biotech company Affichem, which develops small molecules for therapeutic applications. Innovative, translational and longstanding research has ever been a pursuit in his academic career. He is the recipient of the 2023 Schroepfer medal awarded by the American oil Chemist's Society. The Schroepfer Medal recognizes a scientist who has made outstanding advances in the steroid field. The medal was established to honor the memory of George J. Schroepfer, Jr., a leader in the sterol and lipid field for more than 40 years.
Research Interests
Papers共 158 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2024): 106495-106495
Frontiers in oncology (2024): 1414992-1414992
The Journal of steroid biochemistry and molecular biology (2023): 106396-106396
Steroids (2023): 109242-109242
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2023)
The Journal of steroid biochemistry and molecular biology (2023): 106346-106346
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Author Statistics
#Papers: 155
#Citation: 5498
H-Index: 37
G-Index: 71
Sociability: 6
Diversity: 3
Activity: 36
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