基本信息
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Career Trajectory
Bio
My long-term research goal is to identify factors that enhance response and minimize toxicity to drugs used for the treatment of diseases in children, focusing on an individualized therapeutic strategy. My current translational research focuses on methotrexate and its effect upon the folate pathway, utilizing cellular biomarkers and genetic differences to predict drug efficacy and minimize toxicity in JIA. My work has expanded through key collaborations, to include a mouse model for experimental validation of the work, novel cytokine biomarkers including Nicotinamide Phosphoribosyltransferase (NAMPT), biologic therapeutic drug monitoring in JIA and IBD, and exploration of the folate pathway in patients with Down syndrome.
Research Interests
Papers共 134 篇Author StatisticsCo-AuthorSimilar Experts
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期刊级别
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合作机构
Arthritis care & researchno. 5 (2024): 616-626
Victoria E Rael, Julian A Yano, John P Huizar,Leianna C Slayden, Madeleine A Weiss,Elizabeth A Turcotte, Jacob M Terry, Wenqi Zuo,Isabelle Thiffault,Tomi Pastinen,Emily G Farrow,Janda L Jenkins,
The Journal of experimental medicineno. 8 (2024)
Journal of Pediatric Intensive Care (2023)
HEALTH EXPECTATIONSno. 3 (2022): 1029-1037
semanticscholar(2022)
Cited0Views0Bibtex
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Angelique E Boutzoukas, Rachel Olson,Mary Ann Sellers,Gwenyth Fischer,Chi D Hornik,Omar Alibrahim,Kelechi Iheagwara,Kamal Abulebda,Andora L Bass,Katherine Irby,Anjali Subbaswamy, Elizabeth E Zivick,
Contemporary clinical trials (2022): 107067-107067
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Author Statistics
#Papers: 133
#Citation: 2580
H-Index: 24
G-Index: 48
Sociability: 7
Diversity: 1
Activity: 2
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