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个人简介
Manuel S. Rodriguez obtained his PhD in Microbiology (Pasteur Institute, 1992-1997) at Paris 7 University in the group of Dr Virelizier, and continued most of his carrier in Europe. Manuel was initially interested in the regulation of the host cell-virus interaction and, in particular, in the cellular mechanisms used by some viruses to guarantee their replication and perpetuation. These mechanisms include the capacity of certain viral proteins to modify the activity and half-life of cellular vital proteins. Because of this, his work was oriented towards the study of the role of post-translational modifications of the ubiquitin family and the ubiquitin-proteasome pathway in the regulation of the activity of essential cellular factors such as those involved in transcription, nucleo-cytoplasmic transport and oncogenesis. He was a post-doctoral researcher in Ron T. Hay's lab in the Centre for Biomolecular Sciences (1997-2000), University of St. Andrews (Scotland, UK). Then he joined the French National Scientific Research Center (CNRS) in 2000, C. Dargemont's lab at Jacques Monod Institute (2000-2004). In 2005, he moved to Bilbao where he had the opportunity to work as a group leader at CIC bioGUNE (2005-2012) and Inbiomed (2012-2015), both located in the Basque Country. Rodriguez came back to the CNRS to join the ITAV (Institut for Advaced Technologies in Life Sciences, 2015-2020). Finaly joined the Laboratory of Chemistry of Coordination (LCC-Toulouse) since 2020. Among other roles, Manuel was is founder member and coordinator of the European Networks INPROTEOLYS, PROTEOSTASIS, UPStream and UbiCODE, all dedicated to the study of the intracellular signalling and proteolysis.
研究兴趣
论文共 408 篇作者统计合作学者相似作者
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Scientific Reportsno. 1 (2024)
Scientific Reportsno. 1 (2024): 1-9
JOURNAL OF HEPATOLOGYno. 2 (2024): 232-242
Corentin Bouvier, Rachel Lawrence,Francesca Cavallo,Wendy Xolalpa,Allan Jordan,Roland Hjerpe,Manuel S. Rodriguez
CELLSno. 7 (2024): 578
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVASno. 3 (2024): 166-167
Scientific Reportsno. 1 (2024): 1-9
Scientific reportsno. 1 (2024): 7534-7534
SCIENTIFIC REPORTSno. 1 (2024)
Esther García-García, Maria Carreras-Caballé,Albert Coll-Manzano,Alba Ramón-Lainez, Gisela Besa-Selva,Esther Pérez-Navarro,Cristina Malagelada,Jordi Alberch,Mercè Masana,Manuel J Rodríguez
Frontiers in neuroscience (2024): 1394478-1394478
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