基本信息
浏览量:7
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Professor Macdonald (Mac) Christie is a neuropharmacologist, an internationally renowned electrophysiologist and expert in ion channel and synaptic physiology and pharmacology and the leading basic opioid pharmacologist in the nation. He leads a research team that studies cellular and molecular mechanisms in opioid receptor signaling in pain pathways, the biological basis of adaptations that produce chronic pain and drug dependence. Professor Christie is internationally renowned for his studies on ion channel function and neural network plasticity in nervous system disorders such as chronic pain and drug dependence. His research is fundamentally important given the increasing use of opioids to manage moderate to severe chronic pain is complicated by adverse effects such as tolerance, opioid dependence and in some cases, addiction. Misuse and/or inappropriate prescription of opioids are added problems. Increasing the understanding of mechanisms involved in the generation of chronic pain and in the analgesic and adverse effects of opioids (including why/how opioids produce withdrawal symptoms), will pave the way for developing newer therapies that divert signals toward pathways that produce pain relief but with lower rates of adverse effects.
研究兴趣
论文共 75 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Elke Miess,Arisbel B Gondin,Arsalan Yousuf,Ralph Steinborn,Nadja Mösslein,Yunshi Yang, Martin Göldner, Julia G Ruland,Moritz Bünemann,Cornelius Krasel,MacDonald J Christie,Michelle L Halls,
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn