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Bio
Research Interest
Dr. Ragni has actively pursued, initiated, collaborated, and participated in clinical translational research in congenital hemostasis and thrombosis disorders, serving as chair of clinical trials, prospective epidemiologic, observational, case-control studies, cost-effectiveness analyses, and investigator-initiated new drug trials in hemophilia and VWD. Her research studies were among the first multi-center NIH-funded investigator-initiated studies in hemophilia malignancy (NCI), hemophilia inhibitor formation (NHLBI), hemophilia HIV/HCV infection (NHLBI), hemophilia AIDS therapy (NIAID), and hemophilia adult prophylaxis (NHLBI). She co-chaired the NHLBI State of the Science (SOS) Inhibitor Prevention Trial Working Group (2018), and serves as PI of the Inhibitor Prevention and Eradication Platform Trial (HRSA). She also co-chaired the NHLBI SOS Hemophilia & VWD Subcommittee to design future trials, with three U34 trials funded NHLBI, and the VWDMin NHLBI U01 clinical trial to reduce bleeding in women with VWD, and the VWD-Woman trial prevent VWD postpartum bleeding (Takeda). She has collaborated on multi-center organ transplant HIV trials (NIAID), hemophilia gene therapy trials (NHLBI); VWD genotype-phenotype studies (NHLBI); novel therapeutics (fitusiran (siRNA AT) and hemlibra (emcizumab) and extended half-life protein trials (VIIa, VIII, IX) for hemophilia, and rhIL-11 and recombinant VWF for VWD. She has 9 active NIH grants, two of which she serves as PI; and local PI on 6 ATHN CDC grants.
Research Interests
Papers共 354 篇Author StatisticsCo-AuthorSimilar Experts
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Margaret V. Ragni, Jessica Callis,Nabil Daoud,Brian Hu,Matthew Manuel, Jarren Santos,Jonathan Schwartz, Kenneth D. Friedman,Peter Kouides,Philip Kuriakose,Andrew D. Leavitt,Ming Y. Lim,
Margaret V. Ragni,Henry Mead,Ype P. de Jong,Radoslaw Kaczmarek,Andrew D. Leavitt,Brian Long,Diane J. Nugent,Denise E. Sabatino,Sylvia Fong,Annette von Drygalski, Christopher E. Walsh, Bruce A. Luxon
Blood Advances (2024)
BLOOD (2023): 5351
The Lancet. Haematologyno. 11 (2023): E870-E871
Margaret V Ragni,Guy Young,Glaivy Batsuli, Emily Bisson,Shannon L Carpenter,Stacy E Croteau,Adam Cuker,Randall G Curtis,Michael Denne,Bruce Ewenstein, Amber Federizo,Neil Frick,
Expert review of hematologyno. sup1 (2023): 107-127
Journal of thrombosis and haemostasis : JTHno. 11 (2023): 3033-3044
L. Skeith,P. James,P. Kouides,K. Uminski,L. Duffett,S. Jackson,M. Sholzberg,M. Ragni,A. Cuker, M. O’Beirne, S. Rubinstein,J. Hews-Girard,
Research and Practice in Thrombosis and Haemostasis (2023): 100673-100673
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