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个人简介
Since the start of my career, I gained experience as a translational scientist, orientating my career towards the academic world. Prof. Davide Melisi and Dr. Carmine Carbone introduced me to the understanding of the mechanisms of drug resistance in oncology, where I was involved with work in pancreatic cancer pre-clinical models. During my Ph.D., my mentors Prof. Matteo Fassan and Prof. Aldo Scarpa trained me in the field of pathological anatomy and its relevant role in translational medicine. I developed a deep expertise in the field of Next-Generation Sequencing (NGS) technologies applied to routinely formalin-fixed paraffin-embedded (FFPE) tissue samples. The development of a standardized procedure to establish nucleic acids suitability for NGS had been my first goal. Subsequently my focus was directed on the development of custom DNA based panels to be applied in translational research and diagnostic practice. To date, several panels designed by me are routinely used in molecular diagnostics in the laboratory directed by Prof. Aldo Scarpa. At the same time, I collaborated with several national and international research groups on projects concerning the molecular characterization of different types of tumors. Among them, the collaboration with Prof. Emilio Bria allowed me to deal with lung tumors. while the collaborations with Prof. Aldo Scarpa and Prof. Giuseppe Pelosi introduced me much more deeply into the world of gastroenteropancreatic and lung neuroendocrine tumors. Finally, the close collaboration with Dr. Massimo Milione established in the last two years, led me to work on the molecular characterization of all subtypes of lung cancer.
研究兴趣
论文共 141 篇作者统计合作学者相似作者
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British journal of cancerpp.1-12, (2024)
Francesca Masetto,Andrea Mafficini,Burcu Saka,Ayse Armutlu,Deyali Chatterjee,Kee-Taek Jang,Yoh Zen, Pooja Navale, Matteo Fassan, Carlos E Bacchi, Paola Mattiolo,Michele Simbolo,
The American journal of surgical pathology (2024)
crossref(2023)
LABORATORY INVESTIGATIONno. 3 (2023): S1598-S1598
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Anguraj Sadanandam, Stephan Wullschleger,Costas A. Lyssiotis, Carsten Grötzinger,Stefano Barbi, Samantha Bersani, Jan Körner, Ismael Wafy,Andrea Mafficini, Rita T. Lawlor,Michele Simbolo,John M. Asara,
crossref(2023)
Giovanni Centonze,Patrick Maisonneuve,Michele Simbolo,Vincenzo Lagano,Federica Grillo,Natalie Prinzi,Sara Pusceddu, Loretta Missiato, Marilena Colantuono,Giovanna Sabella,Luisa Bercich,Alessandro Mangogna,
Valentina Angerilli,Giovanna Sabella,Michele Simbolo,Vincenzo Lagano,Giovanni Centonze,Giada Munari,Gianluca Businello,Sara Pusceddu, Matteo Fassan, Massimo Milione
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Michele Simbolo, Nicola Silvestris, Giuseppe Malleo,Andrea Mafficini, Laura Maggino, Alessandra Cocomazzi, Lisa Veghini, Aldo Mombello, Francesco Pezzini, Elisabetta Sereni, Filippo M. Martelli, Anastasios Gkountakos,
Modern Pathologyno. 9 (2023)
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