Magali Seguret - French Institute of Health and Medical Research

基本信息

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职业迁徙

个人简介

My PhD project focuses on the development of a gene editing therapy for cardiac dysfunction in laminopathies. This gene therapy will be validated on engineered cardiac tissues.

研究兴趣

论文共 10 篇作者统计合作学者相似作者

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Cardiomyocytes-derived from NAMPT Deficient Human Induced Pluripotent Stem Cells Exhibit Reduced NAD Pools and Contractility Dysfunction

Charlène Jouve,Andrea Ruiz-Velasco,Ahmed Karoui,Céline Pereira,Lucille Deshayes,Magali Seguret,Mathias Mericskay,Jean-Sébastien Hulot

Archives of cardiovascular diseasesno. 6-7 (2024): S211-S211

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A Versatile High-Throughput Assay Based on 3D Ring-Shaped Cardiac Tissues Generated from Human Induced Pluripotent Stem Cell Derived Cardiomyocytes

Magali Seguret,Patricia Davidson,Stijn Robben,Charlene Jouve,Celine Pereira, Quitterie Lelong,Lucille Deshayes,Cyril Cerveau,Mael Le Berre, Rita S. Rodrigues Ribeiro,Jean-Sebastien Hulot

ELIFE（2024）

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Hsa-Mir-548v Controls the Viscoelastic Properties of Human Cardiomyocytes and Improves Their Relaxation Rates

Eva Vermersch, Salome Neuvendel,Charlene Jouve,Andrea Ruiz-Velasco,Celine Pereira,Magali Seguret, Marie-Elodie Cattin-Messaoudi, Sofia Lotfi,Thierry Dorval, Pascal Berson,Jean-Sebastien Hulot

JCI INSIGHT（2024）

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Depressed Mitochondrial Function in Cardiomyopathy Caused by LMNA Gene Mutation Highlighted in Patient-Derived Ipsc-Cms

Magali Seguret,Charlène Jouve,Lucille Deshayes,Céline Pereira,Andrea Ruiz-Velasco,Zeina R. Al Sayed,Karim Wahbi,Antoine Muchir,Gisèle Bonne,Jean-Sébastien Hulot

Archives of cardiovascular diseasesno. 6-7 (2024): S211-S212

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The H222P-Lamin Mutation Induces Heart Failure Via Impaired Mitochondrial Calcium Uptake in Human Cardiac Laminopathy

J. Hulot,M. Seguret,C. Jouve,L. Deshayes,A. Ruiz-Velasco,C. Pereira,K. Wahbi,A. Muchir,G. Bonne

EUROPEAN HEART JOURNAL（2024）

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Rod-shaped Micropatterning Enhances the Electrophysiological Maturation of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells

Zeina R. Al Sayed,Charlene Jouve,Magali Seguret,Andrea Ruiz-Velasco,Celine Pereira,David-Alexandre Tregouet,Jean-Sebastien Hulot

STEM CELL REPORTS（2024）

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Myocardial Disarray Drives Metabolic Inefficiency in Human Cardiomyocytes

Charlene Jouve,Andrea Ruiz-velasco,Erminia Donnarumma,Remi Le Borgne,Iman Momken,Celine Pereira,Magali Seguret,Eva Vermersch,Elodie Vimont,Ivan Nemazanyy,jean-marc Verbavatz,Luc Bertrand,Timothy Wai,Mathias MERICSKAY,Jean-Sebastien Hulot

biorxiv（2024）

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A Novel High-Throughput Assay to Produce Ring-Shaped 3D Cardiac Tissues from Human Induced Pluripotent Stem Cells

Magali Seguret,Patricia Davidson,Stijn Robben,Charlène Jouve,Céline Pereira,Cyril Cerveau,Maël Le Berre, Ana Rita Ribeiro,Jean-Sébastien Hulot

Archives of Cardiovascular Diseases Supplementsno. 2 (2023): 192-193

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CRISPR/Cas9 Genome Editing for a Correction of LMNA P.h222p Mutation Using Human-Induced Pluripotent Stem Cells (Hipscs)

Magali Seguret,Charlene Jouve,Zeina R. Al Sayed,Céline Pereira,Karim Wahbi,Antoine Muchir,Gisèle Bonne,Jean-Sébastien Hulot

Archives of Cardiovascular Diseases Supplementsno. 2 (2022): 188

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Cardiac Organoids to Model and Heal Heart Failure and Cardiomyopathies

Magali Seguret,Eva Vermersch,Charlene Jouve,Jean-Sebastien Hulot

Biomedicinesno. 563 (2021): 563

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