基本信息
浏览量:270
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
个人简介
Prof. Oren was born in Poland and immigrated to Israel as a child in 1950. He received his MSc degree in microbiology from Tel Aviv University in 1970, and his PhD in molecular virology from the Weizmann Institute of Science in 1978. He did postdoctoral work at Princeton University and at SUNY-Stony Brook. In 1981, he joined the Weizmann Institute where he holds the Andre Lwoff Professorial Chair in Molecular Biology. Prof. Oren has held a number of senior positions at the Institute: he served as Director of the Leo and Julia Forchheimer Center for Molecular Genetics, Chairperson of the Council of Professors and of the Senior Promotions Committee, and, from 1999 to 2003, was Dean of the Faculty of Biology.
Prof. Moshe Oren has spent much of his career studying a key player in molecular cancer control—the tumor suppressor gene called p53. In the early 1980s, he cloned p53, in other words, he determined the sequence of its genetic letters, which has provided the foundation for much of the subsequent p53 research worldwide. Prof. Oren also obtained some of the earliest evidence that p53 is indeed a tumor suppressor and was the first to prove that this gene causes apoptosis, the natural process that leads to cell death. These findings have enabled physicians to develop innovative therapeutic strategies, including the first clinically approved anti-cancer gene therapy. Prof. Oren's current work deals with understanding the mechanisms that govern the activity of p53 in normal and in cancer cells. Additional research topics include the involvement of micro-RNAs—tiny bits of encoded genetic material that regulate protein production—in cancer. He is also studying the impact of the ubiquitin-proteasome system, which regulates the protein turnover in the cell, on networks of cancer-regulatory proteins.
His numerous awards include the Leukemia Society of America Scholarship (1985-1990), the Feher Award for Medical Research (1993), the Abisch-Frenkel Prize for Excellence in the Life Sciences (1999), the Sergio Lombroso Award in Cancer Research, the Lombroso Prize for Cancer Research (2002), the Harvey Lectureship of NY (2002), the EMET Prize in Biology (2003), a Merit Award of the National Cancer Institute (2003), and the Israel Prize in 2008 for biochemistry. He serves on the editorial boards of several leading scientific journals and is a member of the Israel Academy of Sciences and Humanities and a Foreign Honorary Member of the American Academy of Arts and Sciences and of the Academia Europeae.
Prof. Oren and his wife Rachel, also a graduate of the Weizmann Institute, have four children and three grandchildren. In the little time that is not devoted to science, Prof. Oren likes to listen to classical music and take nature hikes.
研究兴趣
论文共 522 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Lisha Qiu Jin Lim,Lital Adler,Emma Hajaj,Leandro R Soria,Rotem Ben-Tov Perry,Naama Darzi, Ruchama Brody,Noa Furth,Michal Lichtenstein, Elizabeta Bab-Dinitz,Ziv Porat, Tevie Melman,
Nature metabolismpp.1-1, (2024)
Kathrin Boepple,Yaara Oren, Whitney S. Henry,Meng Dong,Sandra Weller, Julia Thiel,Markus Kleih,Andrea Gaissler, Damaris Zipperer,Hans-Georg Kopp,Yael Aylon,Moshe Oren,
Ruqaia Abbas, Oliver Hartmann, Dorin Theodora Asiss, Rabab Abbas, Julia Kagan, Hyoung-Tae Kim,Moshe Oren,Markus Diefenbacher,Amir Orian,Sarit Larisch
Linda Bojmar,Constantinos P Zambirinis,Jonathan M Hernandez,Jayasree Chakraborty, Lee Shaashua,Junbum Kim, Kofi Ennu Johnson, Samer Hanna, Gokce Askan, Jonas Burman,Hiranmayi Ravichandran,Jian Zheng,
Nature medicinepp.1-11, (2024)
Ira Kogan,Naomi Goldfinger,Michael Milyavsky,Merav Cohen,Igor Shats, Gabriele Dobler,Helmut Klocker,Bohdan Wasylyk, Maureen Voller,Tilly Aalders, Jack A. Schalken,Moshe Oren,
crossref(2023)
crossref(2023)
Matthias Gutekunst,Thomas Mueller,Andrea Weilbacher,Michael A. Dengler, Jens Bedke,Stephan Kruck,Moshe Oren, Walter E. Aulitzky,Heiko van der Kuip
crossref(2023)
Ira Kogan,Naomi Goldfinger,Michael Milyavsky,Merav Cohen,Igor Shats, Gabriele Dobler,Helmut Klocker,Bohdan Wasylyk, Maureen Voller,Tilly Aalders, Jack A. Schalken,Moshe Oren,
crossref(2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn