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职业迁徙
个人简介
The overall goal of the Onishi lab is to understand the fundamental core mechanisms of eukaryotic cell division that have been conserved throughout the evolution from the last eukaryotic common ancestor. To this end, the lab currently uses the unicellular model green alga Chlamydomonas reinhardtii, which is evolutionarily close to plants yet divide like animals by forming a cleavage furrow. Strikingly, unlike animals, this organism does not have a non-muscle type-II myosin that has been believed to be essential for furrowing. In fact, animals, fungi, slime molds, and related species are the exceptions in that they have this myosin motor protein, and the vast majority of the eukaryotes divide by some mechanism that we don't fully understand. Our work aims to understand how the cells without type-II myosin manage to form a cleavage furrow, which should shed light on the questions such as:
(1) How did the ancestral cells divide?
(2) What was the evolutionary advantage of type-II myosin when it emerged in the select lineage?
(3) How did the unique evolution into modern land plants happen?
(1) How did the ancestral cells divide?
(2) What was the evolutionary advantage of type-II myosin when it emerged in the select lineage?
(3) How did the unique evolution into modern land plants happen?
研究兴趣
论文共 53 篇作者统计合作学者相似作者
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bioRxiv : the preprint server for biology (2024)
Megan H. Liu, Ze-Yi Han, Yaning Yuan, Katrina DeWitt,Daniel J Wieczynski, Kathryn M Yammine,Andrea Yammine,Rebecca Zufall,Adam Siepielski, Douglas Chalker,Masayuki Onishi, Fabio A Machado,
biorxiv(2024)
bioRxiv : the preprint server for biology (2024)
The Chlamydomonas Sourcebookpp.433-445, (2023)
Lianyong Wang,Weronika Patena,Kelly A Van Baalen,Yihua Xie, Emily R Singer,Sophia Gavrilenko,Michelle Warren-Williams,Linqu Han,Henry R Harrigan, Linnea D Hartz,Vivian Chen,Vinh T N P Ton,
Li Zhu,Qin Li, Stephen H.K. Wong, Min Huang,Brianna J. Klein,Jinfeng Shen, Larissa Ikenouye,Masayuki Onishi,Dominik Schneidawind,Corina Buechele,Loren Hansen,Jesús Duque-Afonso,
crossref(2023)
Claire D McWhite,Wisath Sae-Lee,Yaning Yuan,Anna Mallam, Nicolas A Gort-Frietas,Silvia Ramundo,Masayuki Onishi,Edward M Marcotte
biorxiv(2022)
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