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He developed novel gene therapy approaches to cardiovascular diseases with adeno-associated viral vectors AAV and invented hypoxia sensitive gene switches for gene therapies The AAV-gene switch work has expanded for hemorrhage control for hemophila and supported by a grant from the US Army for automatic cessation of battlefield bleeding . He holds patents for producing cardiac stem cells and for antisense RNA inhibition of ACE and for novel beta blockers With his colleague YL Tang,he discovered that stem cells have paracrine effects .They developed cardiac stem cells for human toxicology studies, and SDF-1 for reducing myocardial infarction injury in the heart . He is also an advocate for patients with rare diseases. He has received awards and grants for research including an NIH Merit Award and Howard Hughes Medical Institute award. Dr Phillips is a Fellow of the American Association for Science, and Fellow of the American Heart Association and member of the National Academy of Inventors .
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Cellular and Molecular Biology of the Renin-Angiotensin Systempp.97-130, (2018)
Molecular and cellular endocrinology (2018): 148-154
Maria Claudia Irigoyen,M I Phillips,E M Oliveira,T G Fernandes,N Y Hashimoto,G F Mota, Marco Aurelio Amadeu,Yonathan F Melman,Ravi Shah,Saumya Das, Stephen Y Chan,Sophia Dyer,
mag(2015)
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