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Bio
My research work in recent years has focused on understand the importance of oxygen sensing in plants (recent review here), and discovering the roles that the N-degron pathways of ubiquitin-mediated proteolysis play in regulating plant development and responses to the environment (recent review here). This included the discovery that the pathway controlled by the E3 ligase PRT6 acts as a molecular mechanism for oxygen sensing in flowering plants (Nature 2011), and as a nitric oxide sensing mechanism (Molecular Cell, 2014, Nature Communications, 2019). We showed that the pathway controls development (PNAS 2009), response to multiple abiotic (Current Biology 2017) and biotic stresses (BMC Plant Biology 2016, New Phytologist 2018, Plant Direct 2019), and that oxygen-sensing through this pathway is a component of skotomorphogenesis (Current Biology 2015) and mitochondrial retrograde signalling (Current Biology 2022). The pathway influences the oxygen-dependent half-life of key nuclear regulatory proteins (Nature Communications 2018, New Phytologist 2021), and manipulation of the pathway enhances water-logging tolerance in barley (Plant Biotechnology Journal 2016). The oxygen-sensing pathway contributes to geographical adaptation to humidity (Science Advances 2022), and is a key component of adaptation to absolute altitude (Nature 2022).
Research Interests
Papers共 145 篇Author StatisticsCo-AuthorSimilar Experts
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Aida Kozlic,Nikola Winter,Theresia Telser, Jakob Reimann, Katrin Rose,Lilian Nehlin,Sophie Berckhan,Gunjan Sharma,Charlene Dambire,Tinne Boeckx,Michael J. Holdsworth,Andreas Bachmair
African Journal of Food, Agriculture, Nutrition and Developmentno. 2 (2022): 19471-19495
Anne-Marie Labandera,Hannah M Tedds,Mark Bailey,Colleen Sprigg,Ross D Etherington, Olunwatunmise Akintewe, Geetika Kalleechurn,Michael J Holdsworth,Daniel J Gibbs
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Author Statistics
#Papers: 141
#Citation: 12183
H-Index: 58
G-Index: 110
Sociability: 6
Diversity: 3
Activity: 62
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