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Bio
Dr. Mark Groudine studies how cells turn genes on and off, and how changes to these processes can lead to cancer. He has shown that the packaging and 3D organization of DNA changes by type of tissue, and that this influences gene expression. Dr. Groudine’s work led to the discovery of a region of DNA that helps to control the expression of hemoglobin, the oxygen-transporting protein in red blood cells. A specific type of anemia, called thalassemia, occurs when this region of DNA is missing. Similar DNA regions have been discovered for other genes and have been implicated in other diseases, including a type of lymphoma.
Research Interests
Papers共 301 篇Author StatisticsCo-AuthorSimilar Experts
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crossref(2021)
NATURE COMMUNICATIONSno. 1 (2021): 2850-2850
bioRxiv (Cold Spring Harbor Laboratory)pp.1-18, (2020)
Gene Amplification in Mammalian Cellspp.397-404, (2020)
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Author Statistics
#Papers: 302
#Citation: 46703
H-Index: 104
G-Index: 215
Sociability: 7
Diversity: 1
Activity: 0
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