基本信息
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职业迁徙
个人简介
I am a Research Fellow and Clinical Haematologist with a specialist interest in Myelodysplastic syndromes and Acute Myeloid Leukaemia (AML). These are oligoclonal myeloid malignancies where genetically distinct clones can result in differences in leukaemia cell function within individual patients. I am investigating how clonal heterogeneity affects the biology of leukaemia stem cells in MDS and AML, in particular response to novel anti-leukaemic therapies. I am integrating genomic and functional approaches, including single cell techniques to elucidate clonal structures, epigenetic and transcriptional heterogeneity. My research and clinical interest converge on the common goal to develop better therapies to MDS and AML patients.
研究兴趣
论文共 74 篇作者统计合作学者相似作者
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HemaSphereno. S3 (2023): e7326920-e7326920
Sarah Mackie,Matthew D Sadler,Douglas R. A. Silveira, H Assefa-Kebede, Pilar Casares Aláez,Giorgio Napolitani,Aleksandar Ivetic,Daniel I Bromage,Lynn Quek
HemaSphereno. S3 (2023): e4809599-e4809599
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Journal of Clinical Haematologyno. 1 (2023): 20-35
Dominique Sternadt,Diego Pereira-Martins,Douglas R. A. Silveira,Isabel Weinhaeuser,Ming Yang,Prodromos Chatzikyriakou, Pilar Casares Alaez,Emanuele Ammatuna, Lieve Oudejans,Gerwin A. Huls, Christian Frezza,Lynn Quek,
Diego Pereira-Martins,Noortje van Dijk,Isabel Weinhaeuser,Douglas RA Silveira, Juan Coelho Da Silva,Thiago M Bianco,César Alexander Ortiz, Fabiola Traina,Lorena L Figueiredo-Pontes,Emanuele Ammatuna,Lynn Quek,Gerwin A. Huls,
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