Luke Aaron Wiley - Stephen A. Wynn Institute for Vision Research, University of Iowa

基本信息

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职业迁徙

个人简介

A part of an outstanding team of scientists and clinicians at the Institute for Vision Research who are working towards the treatment of inherited retinal dystropies using gene- and cell-based approaches.

研究兴趣

论文共 96 篇作者统计合作学者相似作者

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Transconjunctival Approach for Injection into the Rat Optic Nerve

Elaine Binkley,H Culver Boldt, Lorena Haefeli, Lola P Lozano, Emily Meyering,Luke Wiley, Budd Tucker

Journal of visualized experiments JoVE (2025)

引用0浏览0WOS引用

A Dual AAV Vector Approach for the Treatment of ABCA4-associated Retinal Disease

Erin R. Burnight,Luke A. Wiley,Dalyz Ochoa,Katayoun Varzavand,Seongjin Seo,Ian Han,Robert F. Mullins,Edwin M. Stone,Budd A. Tucker

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 7 (2024)

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Mir-181 Expression and Inhibition: a Potential New Treatment for Dominant Rhodopsin Associated Retinitis Pigmentosa

Renato Jensen, Lorena Haefeli,Luke A. Wiley,Colleen Stein,Jessica L. Fick,Malia Collins,Robert F. Mullins,Ian Han,Edwin M. Stone,Ryan Boudreau,Budd A. Tucker

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 7 (2024)

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The Role of Nicotinamide N-methyltransferase in Choroidal Endothelial Cells: Possible Role in Macular Neovascularization

Emma Mae Navratil,Miles J. Flamme-Wiese, Adnan Khan,Xiuying Liu,Luke A. Wiley,Edwin M. Stone,Budd A. Tucker,Robert F. Mullins

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 7 (2024)

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Transplantation of Cgmp Compliant Ipsc-Derived Retinal Progenitor Cells

Laura R. Bohrer,Luke A. Wiley,Allison T. Wright,Louisa Affatigato,Robert F. Mullins,Edwin M. Stone,Ian Han,Budd A. Tucker

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 7 (2024)

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Characterization and Gene -Based Treatment of a Novel CRISPR-Cas9 Generated Mak-deficient Rat Model of Photoreceptor Degeneration

Lorena Haefeli,Luke A. Wiley,Cathryn Cranston,Heather Daggett,Ian Han,Edwin M. Stone,Robert F. Mullins,Budd A. Tucker

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE（2024）

引用0浏览0引用

Characterization of a Novel Pde6b-deficient Rat Model of Retinal Degeneration and Treatment with Adeno-Associated Virus (AAV) Gene Therapy

Ian C. Han,Luke A. Wiley,Dalyz Ochoa,Mallory J. Lang,Brynnon E. Harman,Katie M. Sheehan,Robert F. Mullins,Edwin M. Stone,Budd A. Tucker

GENE THERAPY（2023）

引用4浏览0WOSNATURE引用

CRISPRi-Mediated Treatment of Dominant Rhodopsin-Associated Retinitis Pigmentosa

Erin R. Burnight,Luke A. Wiley,Nathaniel K. Mullin,Malavika K. Adur,Mallory J. Lang,Cathryn M. Cranston,Chunhua Jiao,Stephen R. Russell,Elliot H. Sohn,Ian C. Han,Jason W. Ross,Edwin M. Stone,Robert F. Mullins,Budd A. Tucker

The CRISPR Journalno. 6 (2023): 502-513

引用2浏览0WOS引用

The Degree of Adeno-Associated Virus-Induced Retinal Inflammation Varies Based on Serotype and Route of Delivery: Intravitreal, Subretinal, or Suprachoroidal

Luke A. Wiley,Timothy M. Boyce, Emily E. Meyering,Dalyz Ochoa,Katie M. Sheehan,Edwin M. Stone,Robert F. Mullins,Budd A. Tucker,Ian C. Han

Human Gene Therapyno. 11-12 (2023): 530-539

引用7浏览0WOS引用

Biocompatibility of Human Induced Pluripotent Stem Cell–Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats

Ian C. Han,Laura R. Bohrer,Katherine N. Gibson-Corley,Luke A. Wiley,Arwin Shrestha,Brynnon E. Harman,Chunhua Jiao,Elliott H. Sohn,Rion Wendland,Brittany N. Allen,Kristan S. Worthington,Robert F. Mullins,Edwin M. Stone,Budd A. Tucker

CELL TRANSPLANTATION（2022）

引用13浏览0WOS引用

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