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We work at understanding the functioning of receptors that mediate fast synaptic transmission, and focus on two classes of ion channels in the nicotinic superfamily, nicotinic and glycine receptors. Different types of nicotinic receptors (which are all excitatory and activated by the transmitter acetylcholine) mediate the initiation of muscle contraction by the peripheral terminals of motor neurones in the spinal cord and the regulation of involuntary bodily functions, such as blood pressure at the level of autonomic ganglia. Yet other forms of nicotinic receptors are present in the brain and are affected by the nicotine in tobacco smoke.
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Papers共 139 篇Author StatisticsCo-AuthorSimilar Experts
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British Journal of Pharmacologyno. S2 (2023): S145-S222
BRITISH JOURNAL OF PHARMACOLOGY (2023): S145-S222
British journal of pharmacologyno. S1 (2021): S157-S245
IUPHAR/BPS Guide to Pharmacology CITEno. 3 (2021)
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