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Bio
Research
Helminth secretomes and how they orchestrate a parasitic existence.
Helminth vaccine discovery and development.
Helminth-derived anti-inflammatory proteins.
My group is primarily interested in the secretomes of parasitic helminths, and the subsequent use of worm secreted proteins as therapeutics and diagnostic tools. Major projects in the lab include;
1. Use of worm proteins as novel anti-inflammatories for treating a range of autoimmune and allergic disorders of humans.
2. Clinical trials to assess the therapeutic properties of iatrogenic hookworm infection in human inflammatory and metabolic diseases
3. Use of proteome microarrays to discover vaccine and diagnostic antigens for human helminth infections.
4. Understanding the mechanisms by which parasitic helminths suppress (and in some cases, drive) immunopathology with a particular emphasis on extracellular proteins and vesicles.
In addition to my role at JCU, I serve as deputy editor of the International Journal for Parasitology.
Research Interests
Papers共 486 篇Author StatisticsCo-AuthorSimilar Experts
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引用量
主题
期刊级别
合作者
合作机构
Mikhael D Manurung,Friederike Sonnet,Marie-Astrid Hoogerwerf,Jacqueline J Janse,Yvonne Kruize,Laura de Bes-Roeleveld, Marion König,Alex Loukas,Benjamin G Dewals, Taniawati Supali,Simon P Jochems, Meta Roestenberg,
Nature communicationsno. 1 (2024): 5960-5960
Nature Immunologyno. 4 (2024): 1-1
Tiziano Raffaelli,David T. Wilson,Sebastien Dutertre,Julien Giribaldi,Irina Vetter, Samuel D. Robinson, Ashvriya Thapa, Antin Widi,Alex Loukas,Norelle L. Daly
Journal of Biological Chemistryno. 4 (2024): 107203-107203
NATURE IMMUNOLOGY (2024)
Trends in Parasitologyno. 5 (2024): 386-400
INTERNATIONAL JOURNAL FOR PARASITOLOGYno. 8 (2023): 391-392
Folia parasitologica (2023)
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Author Statistics
#Papers: 488
#Citation: 25742
H-Index: 88
G-Index: 141
Sociability: 7
Diversity: 4
Activity: 259
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