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个人简介
Dr. Staudt pioneered the use of gene expression profiling to discover molecularly and clinically distinct cancer subtypes and to predict response to therapy. He defined molecular subtypes of lymphoma that were previously unrecognized but are now viewed as distinct diseases that arise from different stages of B cell differentiation, utilize different oncogenic mechanisms and offer new therapeutic targets. To develop new treatments for lymphoid malignancies, Staudt’s laboratory uses various high-throughput approaches, including cancer gene resequencing, RNAi/CRISPR-based genetic screens, and combinatorial small molecule screens. The laboratory also conducts genomic investigations within therapeutic trials of targeted agents in lymphoma to define mechanisms of response and resistance.
研究兴趣
论文共 657 篇作者统计合作学者相似作者
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Jaewoo Choi,Michele Ceribelli,James D. Phelan,Björn Häupl,Da Wei Huang,George W. Wright,Tony Hsiao, Vivian Morris,Francesco Ciccarese,Boya Wang, Sean Corcoran,Sebastian Scheich,
Cancer Researchno. 6_Supplement (2024): 3913-3913
Cell Reportsno. 4 (2024): 114105-114105
Zhining Wang,Tanja M Davidsen, Gina R Kuffel, KanakaDurga Addepalli,Amanda Bell,Esmeralda Casas-Silva, Hayley Dingerdissen,Keyvan Farahani, Andrey Fedorov,Sharon Gaheen,Robert L Grossman, Ron Kikinis,
Cancer research (2024)
Andrea J Radtke, Ekaterina Postovalova, Arina Varlamova, Alexander Bagaev, Maria Sorokina, Olga Kudryashova, Mark Meerson, Margarita Polyakova, Ilia Galkin, Viktor Svekolkin, Sergey Isaev, Daniil Wiebe,
Cancer cellno. 3 (2024): 444-463.e10
James D. Phelan,Sebastian Scheich,Jaewoo Choi,George W. Wright,Bjorn Haupl,Ryan M. Young, Sara A. Rieke, Martine Pape,Yanlong Ji,Henning Urlaub,Arnold Bolomsky,Carmen Doebele,
CANCER CELLno. 2 (2024): 238-252.e9
Takaomi Sanda, Jeffrey W. Tyner,Alejandro Gutierrez,Vu N. Ngo,Jason Glover,Bill H. Chang, Arla Yost,Wenxue Ma,Angela G. Fleischman,Wenjun Zhou,Yandan Yang,Maria Kleppe,
crossref(2023)
crossref(2023)
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S424-S425
Suyasha Roy,Min Ren, Steve Christensen,Peng Li,Rosanne Spolski,James Phelan,Louis Staudt,Warren J. Leonard
Journal of Immunologyno. 1 (2023): 243.01-243.01
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Hematological Oncologyno. S2 (2023): 44-46
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