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个人简介
In the Powrie Lab, my research focuses on host-microbe interactions that regulate health and disease. The gut is the primary site of host-commensal symbiosis, but disequilibrium can drive inflammation and damaging systemic immune responses. Indeed, this gut-joint axis has been implicated in inflammatory arthritis, and imbalances in the microbial community have been described in patients. As a part of the Inflammatory Arthritis Microbiome Consortium, cross-disciplinary approaches in next-generation sequencing, multi-omic analyses, and microbiota cultivation will be integrated into experimental systems. The ultimate goal of this research is to identify novel paradigms of microbiota-regulated immune responses, with the potential for novel diagnostic markers and therapeutic interventions.
研究兴趣
论文共 11 篇作者统计合作学者相似作者
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India Brough,Kelsey Thompson, Ciara Latore,Frank Penkava, Chelsea Regan,Claire Pearson,Hui Shi,Anna Ridley,Davide Simone,Lilian Lam,Samuel Bullers, Caroline Moussa,
Discovery immunologyno. 1 (2024): kyae005-kyae005
SCIENCE TRANSLATIONAL MEDICINEno. 706 (2023): eabn4722-eabn4722
crossref(2020)
Cell host & microbeno. 2 (2018): 296-307.e7
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作者统计
#Papers: 11
#Citation: 925
H-Index: 6
G-Index: 7
Sociability: 4
Diversity: 2
Activity: 4
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