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Bio
My research focuses on O-glycans, a sugar that your body makes. In my lab, we’ve found O-glycans are important in the development of the blood and lymphatic vascular system. Without this sugar, the body doesn’t know if it should grow blood vessels or pieces of the lymphatic system, or how to connect them properly. This can lead to many diseases such as cancer metastasis and fatty liver disease. We are working to understand how to prevent these potentially deadly conditions.
My lab also studies the role of glycans on platelets, the smallest blood cell, in the formation of abnormal blood clots, which are the cause of common forms of heart attack and stroke.
In patients with colitis and colorectal tumors, we’ve found that O-glycans are different than in patients with normal intestinal systems. So, we’re also exploring whether abnormalities of this sugar in the intestines might actually cause these diseases—in hopes of using the knowledge we gain to treat these intestinal diseases.
My lab also studies the role of glycans on platelets, the smallest blood cell, in the formation of abnormal blood clots, which are the cause of common forms of heart attack and stroke.
In patients with colitis and colorectal tumors, we’ve found that O-glycans are different than in patients with normal intestinal systems. So, we’re also exploring whether abnormalities of this sugar in the intestines might actually cause these diseases—in hopes of using the knowledge we gain to treat these intestinal diseases.
Research Interests
Papers共 92 篇Author StatisticsCo-AuthorSimilar Experts
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Bin Zuo,Fei Yang,Lulu Huang,Jingjing Han, Tianyi Li,Zhenni Ma,Lijuan Cao, Yun Li,Xia Bai,Miao Jiang,Yang He,Lijun Xia
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Huiping Shi, Liang Gao, Nicole Kirby,Bojing Shao,Xindi Shan, Mariko Kudo,Robert Silasi,John Michael McDaniel,Meixiang Zhou,Samuel McGee, Wei Jing,Florea Lupu,
Bloodno. 13 (2024): 1293-1309
Bin Zuo,Fei Yang,Lulu Huang,Jingjing Han, Tianyi Li,Zhenni Ma,Lijuan Cao, Yun Li,Xia Bai,Miao Jiang,Yang He,Lijun Xia
Cellular and Molecular Gastroenterology and Hepatologyno. 6 (2024): 1039-1061
Lulu Huang,Yuji Kondo,Lijuan Cao,Jingjing Han, Tianyi Li,Bin Zuo, Fei Yang,Yun Li,Zhenni Ma,Xia Bai,Miao Jiang,Changgeng Ruan,
BLOOD ADVANCESno. 4 (2024): 991-1001
Miao Jiang, Fei Yang,Yizhi Jiang,Lu Cheng,Jingjing Han,Jiawei Yi,Bin Zuo,Lulu Huang,Zhenni Ma, Tianyi Li, Lijuan J. Cao,Zhisong Xia,
Bloodno. 12 (2023): 1071-1081
AMERICAN JOURNAL OF HEMATOLOGYno. 8 (2022): E304-E306
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