He previously served as an Elected Member of the HKU Senate, Director of Trauma Service at Queen Mary Hospital, Chairman of the Hospital Authority Central Committee on Trauma Service, Vice-President of the Hong Kong Neurosurgical Society, Deputy Chief of Service in Neurosurgery at Queen Mary Hospital, Division Chief of Neurosurgery at the HKU-Shenzhen Hospital, and Region XVI Chief (Asia-Australasia) of the Advanced Trauma Life Support Programme of the American College of Surgeons.

His clinical and research interests include endoscopic skull base surgery, molecular biology of brain tumour, neuroprotective therapy, medical education, and medical law and ethics. He has supervised 30 postgraduate degree students and published 214 peer-reviewed journal articles, 13 book chapters, three monographs, 130 conference papers, 71 other publications, and delivered 140 invited lectures, with an H-index (Scopus) of 36.