Deanna A Mele - IMED Biotech Unit, AstraZeneca

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论文共 20 篇作者统计合作学者相似作者

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Abstract 7177: Development and validation of clinical pharmacodynamic biomarkers to assess treatment response to HPK1 inhibition and guide dosing decisions

Lin Jia, Yasmin Marikar-Coplin, Jeff Chen,Kevin Xu,Deanna A. Mele, Nadia Luheshi,Sonia Iyer,Anton I. Rosenbaum, Sonia Terrillon

Cancer Researchno. 6_Supplement (2024): 7177-7177

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Degradation of IKAROS prevents epigenetic progression of T cell exhaustion in a novel antigen-specific assay

Tristan Tay,Gayathri Bommakanti, Elizabeth Jaensch, Aparna Gorthi, Iswarya Reddy,Yan Hu,Ruochi Zhang,Aatman Doshi, Sin Lih Tan, Verena Brucklacher-Waldert,Laura Prickett,James Kurasawa,

biorxiv（2024）

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Supplementary Figure 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Aatman S. Doshi,Susan Cantin,Marylens Hernandez,Srimathi Srinivasan,Sharon Tentarelli,Matthew Griffin,Yanjun Wang,Petar Pop-Damkov,Laura B. Prickett, Cecilia Kankkonen,Minhui Shen,Maryann San Martin,

openalex（2023）

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First disclosure of a highly potent and selective HPK1 inhibitor that rescues T cell exhaustion

Deanna A. Mele,Neil Grimster,Gayathri Bommakanti, Jason Shields, Lucas Morrill, Kathryn Giblin, Maryann SanMartin,Yanjun Wang,Minwei Ye, Iswarya KarapaReddy,Kun Song,Theresa Proia,

CANCER RESEARCHno. 7 (2023)

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Abstract 3453: First disclosure of a highly potent and selective HPK1 inhibitor that rescues T cell exhaustion

Deanna A. Mele,Neil P. Grimster,Gayathri Bommakanti, Jason Shields, Lucas A. Morrill,Kathryn Giblin, Maryann SanMartin,Yanjun Wang,Minwei Ye, Iswarya KarapaReddy,Kun Song,Theresa A. Proia,

Cancer Researchno. 7_Supplement (2023): 3453-3453

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Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Aatman S. Doshi,Susan Cantin,Marylens Hernandez, Srimathi Srinivasan,Sharon Tentarelli,Matthew Griffin,Yanjun Wang,Petar Pop-Damkov,Laura B. Prickett,Cecilia Kankkonen,Minhui Shen,Maryann San Martin,

Mol Cancer Ther（2023）

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Supplementary Figure 4 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Aatman S. Doshi,Susan Cantin,Marylens Hernandez,Srimathi Srinivasan,Sharon Tentarelli,Matthew Griffin,Yanjun Wang,Petar Pop-Damkov,Laura B. Prickett, Cecilia Kankkonen,Minhui Shen,Maryann San Martin,

openalex（2023）

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Systemic nano-delivery of low-dose STING agonist targeted to CD103+ dendritic cells for cancer immunotherapy

Aatman S Doshi,Susan Cantin,Laura B Prickett,Deanna A Mele,Mansoor Amiji

Journal of controlled release : official journal of the Controlled Release Society（2022）

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Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer

Alexey Revenko,Larissa S Carnevalli,Charles Sinclair,Ben Johnson,Alison Peter,Molly Taylor,Lisa Hettrick,Melissa Chapman,Stephanie Klein,Anisha Solanki,Danielle Gattis,Andrew Watt,

JOURNAL FOR IMMUNOTHERAPY OF CANCER（2022）

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1405 A CRISPR-Cas9 screen identifies novel epigenetic regulators of T cell exhaustion

Gayathri Bommakanti, Elizabeth Jaensch, Aparna Gorthi, Sin Lih Tan, Verena Brucklacher-Waldert, Steven Criscione,Deanna Mele

Regular and Young Investigator Award Abstracts (2022): A1460-A1461

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