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Career Trajectory
Bio
Lluis Quintana-Murci heads the Unit of Human Evolutionary Genetics (CNRS UMR2000) at the Institut Pasteur (Paris) since 2007, and has been Scientific Director of the Institut Pasteur in 2016-2017. He earned his Ph.D. in Population Genetics at the University of Pavia (Italy), and his MSc in Biology at the University of Barcelona (Spain). He is a population geneticist whose research focuses on the study of the genetic architecture of human populations and the role of genetic diversity in human adaptation. In particular, his laboratory uses genomic data to infer the past demographic history of human populations, with a focus on Africa, and dissect the different forms in which natural selection can act on the human genome. His team is especially interested in exploring the extent to which pathogens have exerted pressures on human innate immunity genes. Over the last years, his team has also adopted a systems immunology approach to understand the different factors (genetic, epigenetic, environmental, etc.) that drive immune response variation between individuals and populations. To this end, they correlate genetic and epigenetic variation in populations with different ancestries and lifestyles with molecular phenotypes (mRNA/miRNAs expression, proteins and metabolites) related to immune responses, to identify mechanisms that have been crucial for our past and present survival against infection. These studies should help to lay the foundations of precision medicine related to infectious and immune-related disorders and vaccine treatment. His laboratory combines molecular and population genetics approaches, with computational modelling and development of new statistical frameworks.
Research Interests
Papers共 283 篇Author StatisticsCo-AuthorSimilar Experts
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Tom Dott,Slobodan Culina, Rene Chemali, Cedric Ait Mansour,Florian Dubois,Bernd Jagla,Jean Marc Doisne,Lars Rogge,Francois Huetz,Friederike Joensson,Pierre-Henri Commere,James Di Santo,
CYTOMETRY PART Ano. 2 (2024): 124-138
medrxiv(2024)
Emma Bloch, Gaëlle Baudemont,Françoise Donnadieu,Laura Garcia,Stéphane Pelleau, SeroPed Study Consortium, Milieu Intérieur Consortium,Lluis Quintana-Murci,Darragh Duffy,Arnaud Fontanet,Michael White
crossref(2024)
Christophe Boetto,Arthur Frouin, Léo Henches, Antoine Auvergne, Yuka Suzuki,Etienne Patin, Marius Bredon,Alec Chiu, Milieu Interieur Consortium,Sriram Sankararaman,Noah Zaitlen, Sean P Kennedy,
Briefings in bioinformaticsno. 4 (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Gaspard Kerner,Guillaume Laval,Anna-Lena Neehus,Zhi Li,Quentin Philippot,Jonathan Bohlen, Laurent Abel, Jacinta Bustamante,Jean-Laurent Casanova,Maxime Rotival,Etienne Patin,Lluis Quintana-Murci
EUROPEAN JOURNAL OF HUMAN GENETICS (2023): 21-21
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bioRxiv (Cold Spring Harbor Laboratory)no. 2 (2023): 100248-100248
M S-medecine Sciencesno. 6-7 (2023): 496-499
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