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个人简介
Listeria monocytogenes is a foodborne pathogenic bacterium for humans and animals causing listeriosis with high levels of mortality, particularly among immunocompromised hosts. The ability to grow under conditions used for food preservation and storage leads to recurrent contamination inside food factories. In addition, L. monocytogenes is able to form biofilms on surfaces contacting with food products causing the spreading of this pathogen throughout the food processing plants. Besides host immunity and number of ingested bacteria, virulence of the strain is an important factor predisposing illness.
Within our group, research about L. monocytogenes aims to investigate: (i) the virulence potential of different clones; (ii) the susceptibility to industrial sanitizers and (iii) proteins differentially secreted in response to stress conditions. The results already available about the exoproteome (planktonic and biofilm state) are being validated through transcriptomic studies and the construction of mutants in specific genes.
The techniques currently optimized for L. monocytogenes are being applied to the study of other foodborne pathogenic bacteria, including Escherichia coli. Other research lines are being conducted through collaborations with other groups within and outside the CBAA, as the effect of probiotics in bacteria virulence (with ITQB).
Over the last years, Luisa Brito has been supervisor of an increasing number of Master’s thesis in the scope of Food Safety and Food Quality. Most of these works are in collaboration with the productive sector contributing to the indispensable transfer of results from University to Food Industry.
研究兴趣
论文共 84 篇作者统计合作学者相似作者
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Acácio Salamandane,John Leech, Rita Almeida, Carolina Silva,Fiona Crispie,Paul D. Cotter,Manuel Malfeito-Ferreira,Luísa Brito
Food Research International (2024): 114556-114556
crossref(2024)
JOURNAL OF CLEANER PRODUCTION (2024): 140052
Biologyno. 10 (2023)
SSRN Electronic Journalno. 4 (2022): 1176-1176
Applied Microbiologyno. 1 (2022): 133-147
Acácio Salamandane, Jessica Oliveira, Miguel Coelho,Beatriz Ramos,Mónica V. Cunha,Manuel Malfeito-Ferreira,Luisa Brito
Applied Microbiologyno. 2 (2022): 367-380
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#Papers: 85
#Citation: 1609
H-Index: 25
G-Index: 34
Sociability: 8
Diversity: 0
Activity: 1
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