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My lab studied the spatial and functional organization of the membrane compartments and associated scaffolding systems of the secretory pathways of plant, algal, yeast and mammalian cells. The membranes of interest included the ER, Golgi apparatus, trans Golgi network (TGN), multivesicular bodies, vacuoles/ lysosomes, plasma membrane, and chloroplasts. The main focus of our recent work has been on obtaining nano-scale, quantitative 3D information of secretory membrane systems and developing chloroplasts in cells preserved by high pressure freezing and analyzed by electron tomography.
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Papers共 315 篇Author StatisticsCo-AuthorSimilar Experts
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semanticscholar(2018)
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Cytoskeleton - Structure, Dynamics, Function and Disease (2017)
Trends in Cell Biologyno. 12 (2017): 885-894
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