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The research of the Ainslie Lab is centered on immune-targeted therapies for the development of vaccines and treatment of infectious and autoimmune diseases. The Ainslie Lab is currently working on influenza vaccines including universal flu vaccines. Additionally, the lab does research on host cell-directed therapeutics for treatment of pathogenic infections including Salmonella enterica and Leishmania donovani. These therapies modulate the host environment to decrease pathogen burden and are thought to help mitigate the emergence of drug resistance as well as enhance the effect of conventional therapies against drug resistant pathogens. Finally, the lab has a focus on antigen specific therapies to treat autoimmune diseases, such as Multiple Sclerosis and Type 1 diabetes. Antigen specific treatments for autoimmune diseases suppress the immune response specifically, rather than universally suppressing the immune system, like many current therapies.
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