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职业迁徙
个人简介
The major accomplishments by the Zhang lab include: 1) revealing the liver-enriched stress sensor CREBH and its functions and molecular mechanisms as a key transcriptional regulator of energy metabolism under the circadian clock or metabolic stress; 2) defining the pathophysiological roles and mechanisms for the primary ER stress sensor IRE1α in B cell development, hepatic lipid metabolism, and macrophage inflammation; 3) uncovering stress mechanisms by which air pollution induces non-alcoholic fatty liver disease (NAFLD), and revealing that the liver is a major target organ of fine airborne particulate matter PM2.5 that is responsible for air pollution-induced NAFLD and Type-2 diabetes in non-obese individuals; 4) identifying the ER lipid-raft protein ERLIN2 as an unconventional oncogenic factor that facilitates luminal breast cancer cell cycle progression, lipid metabolism, and aggressive malignancy.
研究兴趣
论文共 174 篇作者统计合作学者相似作者
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Gioia Heravi, Zhenjie Liu,Mackenzie Herroon,Alexis Wilson,Yang-Yi Fan, Yang Jiang, Nivisa Vakeesan,Li Tao, Zheyun Peng,Kezhong Zhang,Jing Li,Robert S Chapkin,
bioRxiv : the preprint server for biology (2024)
JCI insightno. 6 (2024)
Renjie Hu,Jing Pan,Junyao Zhu, Sanduo Li, Guoqing Zhang,Pengpeng Wang, Wenhui Zhang,Lu Zhang,Li Qin,Ran Li,Weijia Gu,Rucheng Chen,
NANO TODAY (2024)
Trends in Endocrinology & Metabolism (2024)
Renjie Hu,Jing Pan,Junyao Zhu, Sanduo Li, Guoqing Zhang,Pengpeng Wang, Wenhui Zhang,Lu Zhang,Li Qin,Ran Li,Weijia Gu,Rucheng Chen,
Nano Today (2024): 102167
Cell & Bioscienceno. 1 (2024): 1-15
Jianbin Shen,Donghong Ju,Shichao Wu,Jiawei Zhao, Lucynda Pham, Alejandro Ponce,Maozhou Yang,Hui Joyce Li,Kezhong Zhang,Zhe Yang,Youming Xie, Li Li
Research square (2024)
Scientific reportsno. 1 (2024): 9936-9936
Scientific Reportsno. 1 (2023): 1-3
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