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Bio
Kenneth Offit is Chief of the Clinical Genetics Service in the Department of Medicine at Memorial Sloan Kettering Cancer Center (MSKCC). He is also Professor of Medicine and Public Health at Weill Medical College of Cornell University, and Vice Chairman of the Program in Prevention, Control and Population Research at MSKCC.He was awarded an American Cancer Society Career Research Recognition Award and the 2013 ASCO American Cancer Society Award for research in cancer prevention. Dr Offit is a member of the Board of Scientific Counselors of the National Cancer Institute, and of the Evaluation of Genomic Applications in Practice and Prevention working group of the U.S. Centers for Disease Control.
Dr. Offit's research team identified the most common mutation associated with hereditary breast and ovarian cancer in those of Ashkenazi Jewish ancestry. His group also published the first prospective study documenting a decreased risk of breast and ovarian cancer following oophorectomy in women carrying inherited mutations of the BRCA genes, and the first genome wide association study of BRCA2 mutation carriers. Dr Offit's group has discovered or characterized inherited mutations associated with risk of breast, ovarian, colon cancer, non-Hodgkin's lymphoma, and other malignancies. His laboratory currently focuses on utilizing genomic approaches to discover novel mechanisms associated with increased risk for common malignancies, or which modify the risks of known hereditary predispositions.
Dr. Offit's research team identified the most common mutation associated with hereditary breast and ovarian cancer in those of Ashkenazi Jewish ancestry. His group also published the first prospective study documenting a decreased risk of breast and ovarian cancer following oophorectomy in women carrying inherited mutations of the BRCA genes, and the first genome wide association study of BRCA2 mutation carriers. Dr Offit's group has discovered or characterized inherited mutations associated with risk of breast, ovarian, colon cancer, non-Hodgkin's lymphoma, and other malignancies. His laboratory currently focuses on utilizing genomic approaches to discover novel mechanisms associated with increased risk for common malignancies, or which modify the risks of known hereditary predispositions.
Research Interests
Papers共 939 篇Author StatisticsCo-AuthorSimilar Experts
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medRxiv : the preprint server for health sciences (2024)
Xiaohui Sun, Shiv Prakash Verma,Guochong Jia,Xinjun Wang,Jie Ping,Xingyi Guo,Xiao-Ou Shu,Jianhong Chen,Andriy Derkach,Qiuyin Cai,Xiaolin Liang,Jirong Long,
Cancer research (2024)
Genetics in medicine : official journal of the American College of Medical Geneticsno. 7 (2024): 101128-101128
Jonathan Mitchell,Niedzica Camacho,Patrick Shea,Konrad H Stopsack,Vijai Joseph,Oliver Burren,Ryan Dhindsa,Abhishek Nag,Jacob E Berchuck, Amanda O'Neill, Ali Abbasi,Anthony W Zoghbi,
medRxiv : the preprint server for health sciences (2024)
Genetics in Medicine Open (2024): 101836
Nature genetics (2024)
Cancer Researchno. 9_Supplement (2024): PO2-09
Ryan M. Kahn,Pier Selenica,Thomas Boerner,Kara Long Roche,Yonghong Xiao,Tiffany Y. Sia,Anna Maio,Yelena Kemel,Margaret Sheehan, Erin Salo -Mullen,Kelsey E. Breen, Qin Zhou,
Joao Miranda, Priya Dave,Yelena Kemel,Rania Sheikh, Grace Zong,Lina Posada Calderon,Marie Will,Ying L Liu,Michael Walsh,Zsofia K Stadler,Kenneth Offit,Alicia Latham,
European journal of human genetics : EJHGpp.1-5, (2024)
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