Ken-Tye has published more than 250 international journals papers and constantly given invited and keynote talks. He is listed as the highly cited researchers in his research field. Ken-Tye’s research group interests include engineering nanomaterials for biophotonic and nanomedicine applications, nanotoxicity and pharmacokinetics of nanomaterials, fabricating miniaturized microdevices for biological applications, designing nanosensors for biodetection, modelling of microfluidics and plasmonic sensor systems, creating devices for nanophotonics studies, applying triboelectric nanogenerator for drug delivery applications, the developing of RNA delivery platform based on conjugated oligoelectrolytes and applications of wearable technologies.