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My laboratory focuses on elucidating the molecular mechanisms by which general anesthetics act to produce anesthesia and its side effects. Our overall hypothesis is that anesthesia is caused by action on neuronal pentameric ligand-gated ion channels. Anesthesia may result from general anesthetics enhancing the action of inhibitory receptors (GABAA or Glycine receptors), inhibiting the action of excitatory receptors (nicotinic, 5HT3A or glutamate receptors) or a mixture of both actions.
Research Interests
Papers共 139 篇Author StatisticsCo-AuthorSimilar Experts
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期刊级别
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合作机构
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2023)
European journal of medicinal chemistry (2020): 112261-112261
Molecular pharmacologyno. 6 (2019): 615-628
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Author Statistics
#Papers: 143
#Citation: 5480
H-Index: 39
G-Index: 72
Sociability: 6
Diversity: 1
Activity: 0
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