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The main research focus of my lab is to understand the mechanisms governing cell organization and architecture. We are currently addressing how one of the key elements of the cytoskeleton (actin) can initiate filaments formation and how these filaments can then be organized to allow inward bending of the plasma membrane. This invagination process is called endocytosis and allows cells to regulate their cell surface composition in response to environmental signals. We are also aiming to understand how the process of endocytosis is coupled to the invasion and survival properties of the human fungal pathogen Candida albicans.
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
BIOMOLECULESno. 7 (2023): 1098-1098
The Journal of biological chemistryno. 5 (2023): 104712-104712
J. J. Tyler,I. I. Smaczynska-de Rooij, L. Abugharsa, J. S. Palmer, L. P. Hancock,E. G. Allwood,K. R. Ayscough
Access Microbiologyno. 9 (2019)
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