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As a class of pathogens parasites tend to establish chronic infections. This means that they have adapted intricate mechanisms of avoiding host immune responses, limiting tissue damage, and modulating their immediate surrounding to support their presence. By understanding how they adapt themselves to their environment, we stand to learn important information about host tissues they colonize. We have a particular interest in how parasites interfere with and manipulate the host ubiquitin-proteasome system.
We currently focus on two organisms: the malaria parasite, Plasmodium falciparum, and the nematode Trichinella spiralis.
As a class of pathogens parasites tend to establish chronic infections. This means that they have adapted intricate mechanisms of avoiding host immune responses, limiting tissue damage, and modulating their immediate surrounding to support their presence. By understanding how they adapt themselves to their environment, we stand to learn important information about host tissues they colonize. We have a particular interest in how parasites interfere with and manipulate the host ubiquitin-proteasome system.
We currently focus on two organisms: the malaria parasite, Plasmodium falciparum, and the nematode Trichinella spiralis.
研究兴趣
论文共 33 篇作者统计合作学者相似作者
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Harry R. King,Mark Bycroft,Thanh-Binh Nguyen,Geoff Kelly, Alexander A. Vinogradov, Pamela J. E. Rowling,Katherine Stott,David B. Ascher,Hiroaki Suga,Laura S. Itzhaki,Katerina Artavanis -Tsakonas
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 21 (2024): e2322923121-e2322923121
PROTEIN SCIENCE (2023)
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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biorxiv(2022)
Bradley Nash,William F. Gregory, Rhiannon R. White,Anna Protasio,Steve P. Gygi,Murray E. Selkirk,Michael P. Weekes,Katerina Artavanis-Tsakonas
Frontiers in Parasitology (2022)
Maryia Karpiyevich,Katerina Artavanis-Tsakonas
Biomoleculesno. 10 (2020): 1403
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