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Bio
Clauser originated the Spectrum Mill suite of software tools for high-throughput interpretation of discovery-mode LC-MS/MS datasets to provide protein/peptide/PTM identification and quantitation, and he also contributes to its ongoing development with Broad partner Agilent Technologies Inc. Recent software development efforts have focused on detection of single amino acid variant and splice isoforms; scoring the certainty/ambiguity in modification site localization; relative quantitation from isotope encoding experiments (i.e. iTRAQ/TMT and SILAC); false discovery rate calculation; and quality metrics for measuring performance aspects of mass spectrometry, chromatography, spectral interpretation, and sample handling.
Research Interests
Papers共 182 篇Author StatisticsCo-AuthorSimilar Experts
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Noor Jailkhani,Karl R. Clauser, Howard H. Mak,Steffen Rickelt,Chenxi Tian,Charles A. Whittaker,Kenneth K. Tanabe, Stephen R. Purdy,Steven A. Carr,Richard O. Hynes
crossref(2023)
crossref(2023)
Molecular & Cellular Proteomicsno. 6 (2023): 100563-100563
crossref(2023)
Martin Stražar, Jihye Park,Jennifer G Abelin,Hannah B Taylor,Thomas K Pedersen,Damian R Plichta,Eric M Brown,Basak Eraslan, Yuan-Mao Hung,Kayla Ortiz,Karl R Clauser,Steven A Carr,
Noor Jailkhani,Karl R. Clauser, Howard H. Mak,Steffen Rickelt,Chenxi Tian,Charles A. Whittaker,Kenneth K. Tanabe, Stephen R. Purdy,Steven A. Carr,Richard O. Hynes
crossref(2023)
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