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个人简介
Prof. So’s research interest focused on molecular mechanisms of transcriptional regulation and functional genomics in mammalian development and human congenital disorders. He is interested in studying mechanisms of transcription regulation during craniofacial development, including transcription factors (TFs), non-coding RNAs (ncRNAs), enhancers and RNA binding proteins (RBPs) using multi-omics and next-generation sequencing approaches in stem cells and organoids. Multiple projects are available under this theme:
Using functional genomics approach to identify genetic factors for congenital craniofacial malformations
The roles of Irx3/Irx5 genes in craniofacial myogenic development and function
The roles of Irx3/Irx5 genes and their gene regulatory network in neural induction
Study of neurogenic placode formation stages and gene regulatory networks using single-cell RNA-seq and organoid culture
Using functional genomics approach to identify genetic factors for congenital craniofacial malformations
The roles of Irx3/Irx5 genes in craniofacial myogenic development and function
The roles of Irx3/Irx5 genes and their gene regulatory network in neural induction
Study of neurogenic placode formation stages and gene regulatory networks using single-cell RNA-seq and organoid culture
研究兴趣
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Carmen Oi Ning Leung,Yang Yang,Rainbow Wing Hei Leung,Karl Kam Hei So,Hai Jun Guo,Martina Mang Leng Lei, Gregory Kenneth Muliawan,Yuan Gao,Qian Qian Yu,Jing Ping Yun, Stephanie Ma, Qian Zhao,
NATURE COMMUNICATIONSno. 1 (2023): 6699-20
biorxiv(2021)
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