基本信息
浏览量:11
职业迁徙
个人简介
Mechanisms in Membrane Dynamics
A defining feature of cells are membrane bilayers that separate them from their environment and, in eukaryotic cells, delineate intracellular organelles with specialized functions. For cells to live and replicate, they must be able to maintain and expand these membranes. In eukaryotes, the lipid building blocks of membranes are made mostly in the endoplasmic reticulum (ER) and then transported to other organelles from there. While the role of vesicle trafficking for lipid transfer between organelles has long been known, we have only in the last decade begun to appreciate the importance of non-vesicular protein-mediated lipid transfer at so-called membrane contact sites, where two organelles are closely apposed. Indeed, the ER, the main site of lipid synthesis, contacts every other cellular organelle at such sites.
A defining feature of cells are membrane bilayers that separate them from their environment and, in eukaryotic cells, delineate intracellular organelles with specialized functions. For cells to live and replicate, they must be able to maintain and expand these membranes. In eukaryotes, the lipid building blocks of membranes are made mostly in the endoplasmic reticulum (ER) and then transported to other organelles from there. While the role of vesicle trafficking for lipid transfer between organelles has long been known, we have only in the last decade begun to appreciate the importance of non-vesicular protein-mediated lipid transfer at so-called membrane contact sites, where two organelles are closely apposed. Indeed, the ER, the main site of lipid synthesis, contacts every other cellular organelle at such sites.
研究兴趣
论文共 117 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
CURRENT OPINION IN CELL BIOLOGY (2024): 102320-102320
Justin L Korfhage,Neng Wan, Helin Elhan, Lisa Kauffman, Mia Pineda,Devin M Fuller,Abdou Rachid Thiam,Karin M Reinisch,Thomas J Melia
bioRxiv : the preprint server for biology (2023)
Journal of Biological Chemistryno. 3 (2023): 103844-S448
引用0浏览0引用
0
0
Zhouping Hong,Karin Reinisch
crossref(2022)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn