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The ability of our biological tissues to adapt to their mechanical environment, and the ways in which our tissues are well suited for their own mechanical role within the body, is a constant source of wonder to me. I am interested in understanding the mechanical signals that are experienced within the skeleton during different types of physical activity, understanding what features of these signals stimulate bone to adapt its structure, and in developing noninvasive methods to quantify bone strength. One ongoing project examines biomechanical risk factors for bone stress injury in runners. We use high resolution quantitative computed tomography (CT) to image bone microstructure, and use these images to create computational models that simulate bone mechanical behavior. Another project uses a combination of clinical CT images, mechanical cadaver testing, and computational modeling to measure changes in bone strength in individuals with spinal cord injury who are participating in a clinical trial that targets bone health.
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Elsevier eBookspp.3-17, (2023)
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NeuroImage. Clinical (2023): 103414-103414
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Michael J. Matthews,Karen L. Troy,Ricardo A. Battaglino,Nguyen Nguyen,Richard Goldstein,Leslie R. Morse
Osteoporosis Internationalno. 2 (2022): 319-325
SSRN Electronic Journalno. 3 (2022): 101380-101380
PROGRESS IN BIOMEDICAL ENGINEERINGno. 1 (2022)
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