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个人简介
Kameshwar R Ayasolla had his training in Neurobiology, Cancer Biology , and Biochemistry, NEPHROLOGY (Podocyte Biology and Tubular Interstitial injury) and in the biology of ‘In-Utero’ Stress. He has several years of research experience in INDIA, ISRAEL, and PORTUGAL & in UNITED STATES OF AMERICA . His Research Career Started at the Christian Medical College Hospital at Vellore, India (PhD), where he demonstrated a Casein Kinase II like enzyme in monkey cerebellum, with a unique tyrosine kinase like activity towards fibrinogen (the clotting protein). Later working at the prestigious Weizmann Institute, in ISRAEL (1996-’98), with mentor Prof.Ephraim Yavin studied oligo progenitor cell differentiation involvement of p21/WAF1/p27KIP1. During his years at Medical University of South Carolina (MUSC) Charleston SC, United States,(’98-2007) he had the opportunity to establish the inflammatory and oxidative stress issues of Abeta peptide in Alzheimer’s Pathology. Demonstrated the anti-oxidant role of Vitamin E in curbing nitrsoative stress, ROS, as well curb ceramide related stress cascades. In addition, have been partly successful in trying to establish an experimental rat model for Cerebral Palsy addressing term birth related in-utero inflammatory stress issues. Also demonstrated the anti-inflammatory as well as therapeutics of N-Acetyl Cysteine (NAC) in Pre-eclampsia.. Later (2008-2010) as a member of the Collaborative projects at the Department of Chemistry at the prestigious Bar Ilan University Ramat Gan , ISRAEL researching on the development of Novel Therapeutic Peptides for Neuro-inflammatory diseases such as Alzheimer’s, Multiple Sclerosis and Stroke. In year 2010- he spent nearly a year researching on the Bio-informatics issues of Huntington Disease- addressing ER Stress and Unfolded Protein Responses. I joined the Feinstein Institute in year 2011 in Neuropharmacology addressing addictive issues of Alcohol and later shifted to Nephrology and ever until now been addressing kidney disease and related aspects.
研究兴趣
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bioRxiv the preprint server for biology (2023)
Frontiers in neuroscience (2023): 890015
Vinod Kumar,Kamesh Ayasolla,Alok Jha,Abheepsa Mishra,Himanshu Vashistha,Xiqian Lan, Maleeha Qayyum, Sushma Chinnapaka, Richa Purohit,Joanna Mikulak,Moin A Saleem,Ashwani Malhotra,
Pediatric Researchno. 5 (2019): 711-718
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