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个人简介
Dr. Tang was the first person to report the involvement of RNAi machinery in DNA damage repair. In 2008, he reported that knockdown of Dicer, a key component of the RNA interference pathway, induced DNA damage (Tang et al, J Cell Biol). This finding opened up a new research direction in the RNAi field. Recently, Dr. Tang identified a class of small cytosolic dsDNA (scDNA) molecules of in human and mouse cells, scDNA represses cGAS activation by competing with long dsDNA for binding to cGAS and by inducing autophagic degradation of long dsDNA and STING (Liu et al, Cell Rep, 2023).
研究兴趣
论文共 55 篇作者统计合作学者相似作者
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STAR Protocolsno. 2 (2024): 102998-102998
Yu-Wei Luo, Jiang-Peng Zhou,Hongyu Ji,Anqi Zheng,Xin Wang,Zhizheng Dai,Zhicheng Luo, Fang Cao,Xing-Yue Wang, Yunfang Bai,Di Chen,Yueming Chen,
biorxiv(2023)
Medical oncology (Northwood, London, England)no. 8 (2023): 217-15
Autophagyno. 5 (2023): 1186-1188
Buran Chen,Danni Zheng,Conghui Liu,Adheesh Bhandari,Suzita Hirachan, Cuihua Shen,Sumnima Mainali,Huihui Li,Wenjie Jiang, Jie Xu,Xiaohua Zhang,Kaifu Tang,
Jiwei Zuo,Anqi Zheng, Xingyue Wang,Zhicheng Luo,Yueming Chen,Xiaoxiao Cheng,Yuemei Zhao,Xian Zhou,Kai-Fu Tang, Xing Du
Medical Oncologyno. 1 (2023): 1-12
Medical oncology (Northwood, London, England)no. 3 (2023): 1-12
Yang Luo,Jing Zhou,Hongyu Ji, Aiping Zheng, Xiaoju Wang,Zhizheng Dai,Zhicheng Luo, Fuliang Cao,Xingyue Wang, Yong Juan Bai,Di Chen,Yueming Chen,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Cell death & diseaseno. 12 (2023): 846-846
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