基本信息
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Bio
He is the recipient of the Pfizer Award in Enzyme Chemistry, the Penn State Faculty Scholar Medal and is a member of the Editorial Board of the Journal of Biological Chemistry. He has designed and built instruments for transient kinetic analysis and made them available through his company, KinTek Corporation that he founded in 1987. He has established the mechanistic basis for DNA polymerase selectivity during polymerization using modern kinetic methods that he developed. His recent work has shown that the toxicity of nucleoside analogs used to treat AIDS is correlated with their rates of incorporation by the mitochondrial DNA polymerase.
Research Interests
Papers共 373 篇Author StatisticsCo-AuthorSimilar Experts
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Rodrigo Fregoso Ocampo,Jack P. K. Bravo,Tyler Dangerfield, Isabel Nocedal, Samatar Jirde, Lisa M. Alexander, Anjali Das, Sarah Nielsen,Kenneth A. Johnson,Christopher T. Brown,Cristina N. Butterfield, Daniela S. A. Goltsman,
biorxiv(2024)
Journal of Biological Chemistryno. 3 (2024)
Grace N Hibshman,Jack P K Bravo, Matthew M Hooper,Tyler L Dangerfield, Hongshan Zhang,Ilya J Finkelstein,Kenneth A Johnson,David W Taylor
Nature communicationsno. 1 (2024): 3663-3663
The Journal of biological chemistryno. 1 (2023): 102744-102744
Nucleic acids researchno. 13 (2023): 6883-6898
The Enzymes (2023): 107-134
Methods in Enzymology (2023): 461-492
Methods in Enzymology (2023): 131-157
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