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Our laboratory is focused on the molecular mechanisms of chromosome segregation in mitosis and meiosis. We use biochemistry, X-ray crystallography, and cryo-electron microscopy to probe the structure, function, and interactions between proteins involved in meiotic chromosome pairing, crossover initiation and maturation, and chromosome segregation. We also study a novel second messenger-based bacteriophage immunity pathway in bacteria, that incorporates eukaryotic-like HORMA domains in a foreign protein-sensing role.
Our laboratory is focused on the molecular mechanisms of chromosome segregation in mitosis and meiosis. We use biochemistry, X-ray crystallography, and cryo-electron microscopy to probe the structure, function, and interactions between proteins involved in meiotic chromosome pairing, crossover initiation and maturation, and chromosome segregation. We also study a novel second messenger-based bacteriophage immunity pathway in bacteria, that incorporates eukaryotic-like HORMA domains in a foreign protein-sensing role.
Research Interests
Papers共 124 篇Author StatisticsCo-AuthorSimilar Experts
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Erica A Birkholz,Chase J Morgan,Thomas G Laughlin,Rebecca K Lau,Amy Prichard, Sahana Rangarajan, Gabrielle N Meza,Jina Lee,Emily Armbruster,Sergey Suslov,Kit Pogliano,Justin R Meyer,
Science (New York, N.Y.)no. 6704 (2024): 105-112
Jack Houston, Clémence Vissotsky,Amar Deep, Hiro Hakozaki, Enice Crews,Karen Oegema,Kevin D Corbett,Pablo Lara-Gonzalez,Taekyung Kim,Arshad Desai
bioRxiv : the preprint server for biologyno. 7 (2024)
bioRxiv : the preprint server for biology (2024)
Eray Enustun,Emily G Armbruster,Jina Lee, Sitao Zhang,Brian A Yee, Kseniya Malukhina,Yajie Gu,Amar Deep,Jack T Naritomi,Qishan Liang,Stefan Aigner,Benjamin A Adler,
bioRxiv the preprint server for biology (2024)
Chase J Morgan,Eray Enustun,Emily G Armbruster,Erica A Birkholz,Amy Prichard, Taylor Forman, Ann Aindow,Wichanan Wannasrichan, Sela Peters, Koe Inlow, Isabelle L Shepherd, Alma Razavilar,
Proceedings of the National Academy of Sciences of the United States of Americano. 19 (2024): e2321190121-e2321190121
Lydia R Chambers,Qiaozhen Ye,Jiaxi Cai, Minheng Gong,Hannah E Ledvina, Huilin Zhou,Aaron T Whiteley,Raymond T Suhandynata,Kevin D Corbett
Current Biologyno. 11 (2023): 2291-2299.e10
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Author Statistics
#Papers: 126
#Citation: 5208
H-Index: 38
G-Index: 72
Sociability: 7
Diversity: 0
Activity: 2
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