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Bio
Bergeron Lab:
Protein nano-machines are large macromolecular assemblies that perform a mechanical function, such as rotation (bacterial flagellum, ATP synthase), extension/contraction (cytoskeleton elements, pili) or macromolecular transport (protein secretion systems). We use structural methods (cryo-EM, NMR spectroscopy, X-ray crystallography, modeling etc...) combined with biophysical techniques to decipher the structure of these assemblies. Our goal is to exploit this information to understand their mechanism of action, and their assembly. Ultimately, this could be used for the design of nanotechnology devices, as well as for developing new drugs.
Protein nano-machines are large macromolecular assemblies that perform a mechanical function, such as rotation (bacterial flagellum, ATP synthase), extension/contraction (cytoskeleton elements, pili) or macromolecular transport (protein secretion systems). We use structural methods (cryo-EM, NMR spectroscopy, X-ray crystallography, modeling etc...) combined with biophysical techniques to decipher the structure of these assemblies. Our goal is to exploit this information to understand their mechanism of action, and their assembly. Ultimately, this could be used for the design of nanotechnology devices, as well as for developing new drugs.
Research Interests
Papers共 37 篇Author StatisticsCo-AuthorSimilar Experts
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
Mark A. Harrison, Rebecca J. Farthing, Nyasha Allen,Lucy M. Ahern,Kristian Birchall, Michael Bond,Harparkash Kaur,Brendan W. Wren,Julien R. C. Bergeron,Lisa F. Dawson
Katherine H Gibson, Jack M Botting,Natalie Al-Otaibi, Kriti Maitre,Julien Bergeron,Vincent J Starai,Timothy R Hoover
Journal of bacteriologyno. 9 (2023)
Structureno. 6 (2022): 677-+
Saskia E. Bakker,Julien Bergeron,Alok Bharadwaj,David Bhella,Per Bullough, Pak-Lee Chau,Rene A. W. Frank,Arjen J. Jakobi,Agnel Praveen Joseph,Werner Kuhlbrandt, Indrajit Lahiri,Rebbekah Menday,
FARADAY DISCUSSIONS (2022): 229-242
Natalie Al-Otaibi, Atieh Aminian J, Rex Frimpong Anane,Pieter Baatsen,Saskia E Bakker,Julien Bergeron,Alok Bharadwaj,David Bhella,Thomas Braun, Rosaria Brescia,Per Bullough,Daniel K Clare,
Noémie Alphonse,Joseph J Wanford,Andrew A Voak, Jack Gay, Shayla Venkhaya,Owen Burroughs,Sanjana Mathew,Truelian Lee, Sasha L Evans, Weiting Zhao, Kyle Frowde,Abrar Alrehaili,
Cellno. 13 (2022): 2354-2369.e17
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