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Bergeron Lab:
Protein nano-machines are large macromolecular assemblies that perform a mechanical function, such as rotation (bacterial flagellum, ATP synthase), extension/contraction (cytoskeleton elements, pili) or macromolecular transport (protein secretion systems). We use structural methods (cryo-EM, NMR spectroscopy, X-ray crystallography, modeling etc...) combined with biophysical techniques to decipher the structure of these assemblies. Our goal is to exploit this information to understand their mechanism of action, and their assembly. Ultimately, this could be used for the design of nanotechnology devices, as well as for developing new drugs.
Protein nano-machines are large macromolecular assemblies that perform a mechanical function, such as rotation (bacterial flagellum, ATP synthase), extension/contraction (cytoskeleton elements, pili) or macromolecular transport (protein secretion systems). We use structural methods (cryo-EM, NMR spectroscopy, X-ray crystallography, modeling etc...) combined with biophysical techniques to decipher the structure of these assemblies. Our goal is to exploit this information to understand their mechanism of action, and their assembly. Ultimately, this could be used for the design of nanotechnology devices, as well as for developing new drugs.
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论文共 39 篇作者统计合作学者相似作者
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Peter Wotherspoon, Hannah Johnston, David J Hardy, Rachel Holyfield,Soi Bui, Giedrė Ratkevičiūtė,Pooja Sridhar, Jonathan Colburn, Charlotte B Wilson, Adam Colyer,Benjamin F Cooper,Jack A Bryant,
Nature Communicationsno. 1 (2024): 1-15
Journal of visualized experiments : JoVE (2023)
Mark A. Harrison, Rebecca J. Farthing, Nyasha Allen,Lucy M. Ahern,Kristian Birchall, Michael Bond,Harparkash Kaur,Brendan W. Wren,Julien R. C. Bergeron,Lisa F. Dawson
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Journal of bacteriologyno. 9 (2023)
Structureno. 6 (2022): 677-+
Noemie Alphonse,Joseph J. Wanford,Andrew A. Voak, Jack Gay, Shayla Venkhaya,Owen Burroughs,Sanjana Mathew,Truelian Lee,Sasha L. Evans, Weiting Zhao, Kyle Frowde,Abrar Alrehaili,
Cellno. 13 (2022): 2354-2369.e17
Natalie Al-Otaibi, Atieh Aminian J., Rex Frimpong Anane,Pieter Baatsen,Saskia E. Bakker,Julien R. C. Bergeron,Alok Bharadwaj,David Bhella,Thomas Braun, Rosaria Brescia,Per A. Bullough,Daniel K. Clare,
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#Papers: 40
#Citation: 960
H-Index: 18
G-Index: 30
Sociability: 5
Diversity: 3
Activity: 23
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