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个人简介
My main research interest has always been evolution; why do we see so many weird, beautiful forms of life on our planet? There are lots of ways to look at evolution, from morphology to ecology, but I was always captivated by genetics, or what’s in the DNA that makes things the way they are and how does this change to affect morphology and ecology? My first research projects looked at how genetics and development of animals interact to produce the diversity of life we see today. My PhD focused on genome size evolution, specifically by examining the genomic causes of genome size change within a single species, and across a species complex. Most of this variation was due to repetitive DNA (transposons and tandem repeats), with evidence that some of these sequences reside on B-chromosomes with a drastically different GC content to the rest of the genome.
My first postdoc project focused on bird microchromosome evolution, specifically GC content, repeat content, gene content, and secondary DNA structures across bird species. In addition to this comparative genomics project, I am also involved in work on germline restricted chromosomes in birds, how transposons regulate gene expression in fungi, and parasitic nematode genomics.
While my research interests seem broad, the common thread tying it all together is what I like to think of as “genomic oddities”, the more we investigate genomes, the more of these we find. Often, sequences like transposons and secondary DNA structures have important, but poorly understood phenotypic impacts. My current work attempts to integrate the study of these “genomic oddities” into applied outcomes for improving aquaculturally relevant fish species. It is only through considering a combination of these genomic oddities of these that we may gain a sense of understanding of genomic impacts on disease, conservation, evolution, and ecology.
研究兴趣
论文共 12 篇作者统计合作学者相似作者
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Georgia Samuels, Liam Hegarty,Warren Fantham,David Ashton,Julie Blommaert,Matthew J. Wylie,Damian Moran,Maren Wellenreuther
AQUACULTURE (2024): 740782
BMC Biology (2021)
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCESno. 1933.0 (2020): 20201441
user-5d7f3c40530c708f991f6404(2015)
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