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个人简介
The research of my group focusses on the evolution of bacterial pathogens; their origin, transmission and adaptation to selective pressure. I primarily use genomic and phylogenetic approaches to address these, and over the last few years my group has used large-scale population genomics to identify the global origin and routes of spread of many human and animal pathogens. Overlaid on the phylogeny, we look for signatures of adaptation to the host, to antibiotics and to vaccine pressure, most recently developing bacterial genome-wide association approaches to identify genetic determinants responsible for this adaptation. In addition to informatics approaches, we develop and apply genome-wide experimental tools, studying interaction with the host and antimicrobial resistance mechanisms. We have an interest in metagenomics, currently studying the microbiota in the gut, the lung, the nasopharynx and the placenta (which doesn’t have one). We often work at an international level, with many collaborations in Low- and Middle-Income countries.
研究兴趣
论文共 1002 篇作者统计合作学者相似作者
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LANCET MICROBEno. 2 (2024): e151-e163
Rathanin Seng,Chalita Chomkatekaew, Sarunporn Tandhavanant,Natnaree Saiprom, Rungnapa Phunpang,Janjira Thaipadungpanit, Elizabeth M Batty,Nicholas P J Day,Wasun Chantratita,T Eoin West, Nicholas R Thomson,Julian Parkhill,
Nature communicationsno. 1 (2024): 5699-5699
Aidan J. Taylor,Koji Yahara, Ben Pascoe, Seungwon Ko,Leonardos Mageiros, Evangelos Mourkas,Jessica K. Calland, Santeri Puranen,Matthew D. Hitchings, Keith A. Jolley,Carolin M. Kobras, Sion Bayliss,
Tamim Khawaja,Tommi Mäklin,Teemu Kallonen,Rebecca A Gladstone, Anna K Pöntinen,Sointu Mero,Harry A Thorpe,Ørjan Samuelsen,Julian Parkhill,Mateen Izhar, M Waheed Akhtar,Jukka Corander,
Nature communicationsno. 1 (2024): 5196-5196
Aaron Weimann,Adam M Dinan,Christopher Ruis,Audrey Bernut, Stéphane Pont, Karen Brown, Judy Ryan, Lúcia Santos,Louise Ellison, Emem Ukor,Arun P Pandurangan, Sina Krokowski,
Science (New York, N.Y.)no. 6704 (2024): eadi0908-eadi0908
Beth Blane,Kathy E Raven,Nicholas M Brown,Ewan M Harrison,Francesc Coll,Rachel Thaxter,David A Enoch,Theodore Gouliouris,Danielle Leek, Sophia T Girgis, Asha Akram,Marta Matuszewska,
Microbial genomicsno. 4 (2024)
LANCET MICROBEno. 2 (2024): e142-e150
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 17 (2024): e2403206121-e2403206121
Gutno. 6 (2024): 910-921
Tengfei Ma, Ning Xie, Yuan Gao, Jiani Fu, Chun E Tan,Qiu E Yang,Shaolin Wang,Zhangqi Shen,Quanjiang Ji,Julian Parkhill,Congming Wu,Yang Wang,
Nature communicationsno. 1 (2024): 5498-5498
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