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Bio
Proteins are versatile nanostructured biomacromolecules which are used by nature in a multitude of functions: as highly active and selective catalysts, as efficient nanomachines, or as nanostructured materials with superior mechanical, electrical, or optical properties. Though in principle any protein can be conveniently produced by chemical DNA synthesis and expression of the respective gene, the application of proteins in white and red biotechnology is still limited to the naturally found proteins and variants thereof. While we understand in most cases how a single mutation changes the biochemical and biophysical properties of a protein, we are only at the very beginning of understanding the general relationship between sequence, structure, and function. A deep understanding of this relationship would enable us to predict the function of a protein from its sequence, and to design ab initio the sequence of a protein with desired properties and functions.
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Papers共 109 篇Author StatisticsCo-AuthorSimilar Experts
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Introduction to Enzyme Technology Learning Materials in Biosciencespp.39-59, (2024)
Communications biologyno. 1 (2024): 707-707
Alexander S. Behr, Julia Surkamp, Elnaz Abbaspour, Max Haeussler,Stephan Luetz,Juergen Pleiss,Norbert Kockmann,Katrin Rosenthal
PROCESSESno. 3 (2024)
Datenbank-Spektrumpp.1-9, (2024)
Simone Lauterbach, Hannah Dienhart,Jan Range,Stephan Malzacher,Jan-Dirk Spöring,Dörte Rother,Maria Filipa Pinto,Pedro Martins,Colton E. Lagerman,Andreas S. Bommarius, Amalie Vang Høst,John M. Woodley,
Journal of applied crystallographyno. Pt 2 (2023): 565-575
Peptide and Protein Engineering for Biotechnological and Therapeutic Applicationspp.353-370, (2023)
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