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Bio
Jonah is currently the Debbie and Andy Rachleff Distinguished Professor of Neurology. He is a member of the Neuroscience Graduate Program, Vice Chief in the Division of Neuroimmunology and Glial Biology and Co-Director of the Innovation Program for Remyelination and Repair at UCSF.
The Chan laboratory has a long-standing interest in fundamental glial/neuronal interactions and the molecular mechanisms that regulate myelination. Myelination is one of the most exquisite examples of cell-cell interaction found in nature and functions to maximize the efficiency and velocity of action potentials transmitted throughout the nervous system. While much has been learned about the global determinants that generate myelin-forming cells during development, the Chan laboratory is particularly interested in understanding how local environmental cues control the spatiotemporal regulation of differentiation and myelination, including both molecular and biophysical interactions. Identification of an environment that is conducive for myelination could have important implications for efforts aimed at promoting repair and remyelination in the nervous system.
The Chan laboratory has a long-standing interest in fundamental glial/neuronal interactions and the molecular mechanisms that regulate myelination. Myelination is one of the most exquisite examples of cell-cell interaction found in nature and functions to maximize the efficiency and velocity of action potentials transmitted throughout the nervous system. While much has been learned about the global determinants that generate myelin-forming cells during development, the Chan laboratory is particularly interested in understanding how local environmental cues control the spatiotemporal regulation of differentiation and myelination, including both molecular and biophysical interactions. Identification of an environment that is conducive for myelination could have important implications for efforts aimed at promoting repair and remyelination in the nervous system.
Research Interests
Papers共 126 篇Author StatisticsCo-AuthorSimilar Experts
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Thomas O Schrader, Kym I Lorrain, Didier Bagnol, Geraldine C Edu,Alexander Broadhead,Christopher Baccei, Michael M Poon,Karin J Stebbins, Yifeng Xiong, Ariana O Lorenzana,Jonah R Chan,Ari J Green,
ACS chemical neuroscienceno. 3 (2024): 685-698
bioRxiv : the preprint server for biologypp.1-9, (2024)
CELL REPORTS MEDICINEno. 4 (2024)
Ahmed Abdelhak,Christian Cordano,Katie Emberley,Greg Duncan,Sonia Nocera,Kirtana Ananth,Nora Jabassini, Kiarra Ning, Henriette Reinsberg,Frederike Oertel,Alexandra Beaudry-Richard,Jens Kuhle,
Neurologyno. 17_supplement_1 (2024)
Feng Mei, Stephen P J Fancy, Yun-An A Shen,Jianqin Niu,Chao Zhao, Bryan Presley, Edna Miao,Seonok Lee, Sonia R Mayoral,Stephanie A Redmond,Ainhoa Etxeberria,Lan Xiao,
Nature medicine (2024)
Proceedings of the National Academy of Sciences of the United States of Americano. 20 (2023)
Sonia Nocera,Jonah R. Chan
Neuronno. 11 (2023): 1689-1691
MULTIPLE SCLEROSIS JOURNAL (2023): 956-956
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Wendy Xin,Megumi Kaneko,Richard H Roth, Albert Zhang, Sonia Nocera,Jun B Ding,Michael P Stryker,Jonah R Chan
bioRxiv : the preprint server for biology (2023)
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