Joseph Rager - 1Prelude Therapeutics

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论文共 25 篇作者统计合作学者相似作者

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Phase Ib Study of PRT543, an Oral Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor, in Patients with Advanced Splicing Factor-Mutant Myeloid Malignancies

Jan Philipp Bewersdorf,Xiaoli Mi,Bin Lu,Andrew Kuykendall,David Sallman,Manish Patel,Don Stevens,Alexander Philipovskiy,Grerk Sutamtewagul,Lucia Masarova,Gina Keiffer,Amit Verma,Neha Bhagwat,Min Wang, Andrew Moore,Joseph Rager,Diane Heiser,Sunhee Ro, Wan-Jen Hong,Omar Abdel-Wahab,Eytan M. Stein

Leukemiapp.1-5, (2025)

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the Brain Penetrant CDK4/6 Inhibitor, PRT3645, is Highly Effective in Combination with Other Targeted Therapies in Preclinical Models of Breast Cancer, CRC and NSCLC

Yue Zou,Kirsten Gallagher,Srijita Dhar, Andrew Busking,Sarah Pawley,Ryan Holmes,Xiaowei Wu,Min Wang,Joseph Rager,Tom Emm,Stefan Ruepp,Miles Cowart,Andrew Combs,Kris Vaddi,Sandy Geeganage,Peggy Scherle,Sang Hyun Lee

Cancer Researchno. 6_Supplement (2024): 5710-5710

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Preclinical Characterization of PRT7732: A Highly Potent, Selective, and Orally Bioavailable Targeted Protein Degrader of SMARCA2

Artem Shvartsbart,Koichi Ito,Joseph Rager,Michael Hulse,Anjana Agarwal,Komali Vykuntam,Jessica Burtell,Min Wang, Justin Kurian,Miles Cowart,Joy Cote, Nick Stahl,Monisha Sivakumar, Anthony Reichelderfer,Jack Carter,Alexander Grego,Andrew Moore,Neha Bhagwat, Ross Kuskovsky,Shanthi Ganesan,Stefan Ruepp,Tom Emm,Philip Pitis,Corey Basch,Klare Bersch,Yongchun Pan,Song Mei,Raul Leal,John Rose, Dani Roth, Chaoyi Xu,Ganfeng Cao,Kris Vaddi,Sang Hyun Lee,Sandy Geeganage,Andrew Combs,Peggy Scherle

Cancer Researchno. 6_Supplement (2024): 4503-4503

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Figure S3 from PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies

Jack Carter,Michael Hulse,Monisha Sivakumar,Jessica Burtell,Venkat Thodima,Min Wang,Anjana Agarwal,Komali Vykuntam,Jacob Spruance,Neha Bhagwat,Joseph Rager,Bruce Ruggeri,Peggy Scherle,Koichi Ito

openalex（2023）

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Figure S2 from PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies

Jack Carter,Michael Hulse,Monisha Sivakumar,Jessica Burtell,Venkat Thodima,Min Wang,Anjana Agarwal,Komali Vykuntam,Jacob Spruance,Neha Bhagwat,Joseph Rager,Bruce Ruggeri,Peggy Scherle,Koichi Ito

openalex（2023）

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Figure S1 from PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies

Jack Carter,Michael Hulse,Monisha Sivakumar,Jessica Burtell,Venkat Thodima,Min Wang,Anjana Agarwal,Komali Vykuntam,Jacob Spruance,Neha Bhagwat,Joseph Rager,Bruce Ruggeri,Peggy Scherle,Koichi Ito

openalex（2023）

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Abstract B113: Discovery of PRT3789, a First-in-class Potent and Selective SMARCA2 Degrader in Clinical Trials for the Treatment of Patients with SMARCA4 Mutated Cancers

Koichi Ito,Michael Hulse,Anjana Agarwal,Jack Carter,Monisha Sivakumar,Komali Vykuntam,Min Wang,Miles Cowart,Joy Cote,William Gowen-MacDonald, Brian Vidal Torres, Justin Kurian,Neha Bhagwat,Norman Fultang,Alexander Grego,Andrew Moore, Ashley Schwab,Jessica Burtell, Olusola Peace Osinubi,Jacob Spruance,Liang Lu,Philip Pitis,Corey Basch,Klare Bersch,Chaofeng Dai,Raul Leal,Artem Shvartsbart,Ganfeng Cao, Bo Shen, Patrick Wen,Joseph Rager, Ross Kuskovsky, Bob Landman,Tom Emm,Stefan Ruepp, Chunhua Qin, Gina Paris, Jennifer Xavier,Rachel Chiaverelli,Sang Hyun Lee,Sandy Geeganage, Hong Lin,Diane Heiser,Bruce Ruggeri,Naveen Babbar,Andrew Combs,Peggy Scherle

Molecular Cancer Therapeuticsno. 12_Supplement (2023)

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Discovery of PRT3789, a First-in-class Potent and Selective SMARCA2 Degrader in Clinical Trials for the Treatment of Patients with SMARCA4 Mutated Cancers

Koichi Ito,Michael Hulse,Anjana Agarwal,Jack Carter,Monisha Sivakumar,Komali Vykuntam,Min Wang,Miles Cowart,Joy Cote,William Gowen -MacDonald, Brian Vidal Torres, Justin Kurian,Neha Bhagwat,Norman Fultang,Alexander Grego,Andrew Moore, Ashley Schwab,Jessica Burtell, Olusola Peace Osinubi,Jacob Spruance,Liang Lu,Philip Pitis,Corey Basch,Klare Bersch,Chaofeng Dai,Raul Leal,Artem Shvartsbart,Ganfeng Cao, Bo Shen, Patrick Wen,Joseph Rager, Ross Kuskovsky, Bob Landman,Tom Emm,Stefan Ruepp, Chunhua Qin, Gina Paris, Jennifer Xavier,Rachel Chiaverelli,Sang Hyun Lee,Sandy Geeganage, Hong Lin,Diane Heiser,Bruce Ruggeri,Naveen Babbar,Andrew Combs,Peggy Scherle

MOLECULAR CANCER THERAPEUTICSno. 12 (2023)

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Figure S5 from PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies

Jack Carter,Michael Hulse,Monisha Sivakumar,Jessica Burtell,Venkat Thodima,Min Wang,Anjana Agarwal,Komali Vykuntam,Jacob Spruance,Neha Bhagwat,Joseph Rager,Bruce Ruggeri,Peggy Scherle,Koichi Ito

openalex（2023）

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FIGURE 1 from PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies

Jack Carter,Michael Hulse,Monisha Sivakumar,Jessica Burtell,Venkat Thodima,Min Wang,Anjana Agarwal,Komali Vykuntam,Jacob Spruance,Neha Bhagwat,Joseph Rager,Bruce Ruggeri,Peggy Scherle,Koichi Ito

openalex（2023）

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