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个人简介
I’m an electrophysiologist; after completing my degree in Neurobiology I worked with Professor A. Colino in the University Complutense of Madrid, Spain; I become an expert in neuron physiology and patch-clamp technique. I completed my PhD in 2012, during that time I focussed on calcium and potassium currents and their relation to the intrinsic excitability of neurons, publishing in Neuroscience letters (2008); Neuroscience (2010 & 2012) and Journal of Physiology (2014).
In 2013 I joined the laboratory of functional microscopy at Imperial College London led by Professor Julia Gorelik. This gave me the opportunity to be involved in several projects studying nanoscale signalling domains in cardiac myocytes, both rat and human, normal and pathological. I am involved in discovering how the disorganisation of them contributes to arrhythmia. I had been looking at the precise location of voltage gated calcium channels on the cardiomyocyte membrane with nanoscale resolution. With the help of state-of-the-art scanning ion conductance microscopy equipped with “smart patch-clamp” I was able to locate functional channels on cardiomyocyte membrane and study their behaviour under different conditions, publishing part of this results in Circulation Research (2016) as first author. I had extended this study focusing on human cardiomyocytes and I’m currently in the submission process of this research. I have been also involved in different projects, including the role of sympathetic neurons in the regulation of cardiomyocytes, combining my two-background knowledge, which is showing promising results. This year I was given the NHLI Post-doc Supervisor Award, which tells about my readiness to help other people in the Department.
I had also participated in numerous international meetings with posters and oral presentations: Society of Neuroscience conference, 2009, Heart Rhythm Society conference, 2014, AHA Scientific Sessions, 2015, ISHR XXII World Congress, 2016, GRC: Cardiac Arrhythmia Mechanisms, 2017, and Biophysical Society Annual meeting, 2018.
研究兴趣
论文共 46 篇作者统计合作学者相似作者
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BIOCHEMICAL JOURNALno. 5 (2024): 387-403
Circulation researchno. 2 (2023): 120-137
Zoe Kwan,Binoy Paulose Nadappuram, Manton M Leung,Sanika Mohagaonkar, Ao Li, Kumuthu S Amaradasa,Ji Chen,Stephen Rothery, Iyobel Kibreab, Jiarong Fu,Jose L Sanchez-Alonso,Catherine A Mansfield,
Zoe Kwan,Binoy Paulose Nadappuram, Manton M. Leung,Sanika Mohagaonkar, Ao Li, Kumuthu S. Amaradasa,Ji Chen,Stephen Rothery, Iyobel Kibreab, Jiarong Fu,Jose L. Sanchez-Alonso,Catherine A. Mansfield,
CIRCULATION RESEARCHno. 11 (2023): 944-958
K Sri-Ranjan,J L Sanchez-Alonso,P Swiatlowska,S Rothery,P Novak, S Gerlach, D Koeninger, B Hoffmann,R Merkel,M M Stevens, S X Sun,J Gorelik,
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2022): S110-S110
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作者统计
#Papers: 42
#Citation: 877
H-Index: 17
G-Index: 29
Sociability: 5
Diversity: 3
Activity: 49
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