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个人简介
Dr. Jalife enjoys an international reputation as a leader in his field of research, which focuses on bringing sophisticated mathematical and biophysical concepts to increase the understanding of the mechanisms of life-threatening cardiac arrhythmias, from the molecule to the bedside. He and his associates have investigated the molecular mechanisms and nonlinear dynamics of heart rhythm and conduction disturbances. Their studies have provided important insight that has led to reevaluation of classical criteria for the diagnosis of complex arrhythmias, including atrial fibrillation and ventricular fibrillation. Other contributions include studies on the cellular mechanisms of dynamic vagal control of heart rate and atrioventricular conduction and the mechanisms of pacemaker synchronization in the sinoatrial node; non-linear dynamics of excitation and propagation in isolated cardiac tissues; application of video-imaging techniques and the use of transgenic and knockout mice to study wave propagation and spiral wave formation in cardiac muscle; and more recently, the study of the cellular and molecular mechanisms underlying sudden death in inherited arrhythmogenic diseases.
研究兴趣
论文共 668 篇作者统计合作学者相似作者
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Francisco M Cruz,Álvaro Macías,Ana I Moreno-Manuel,Lilian K Gutiérrez,María Linarejos Vera-Pedrosa,Isabel Martínez-Carrascoso,Patricia Sánchez Pérez,Juan Manuel Ruiz Robles,Francisco J Bermúdez-Jiménez,Aitor Díaz-Agustín, Fernando Martínez de Benito, Salvador Arias-Santiago,
Giulio La Rosa,Carlos A Morillo,Jorge G Quintanilla,Adelina Doltra,Lluis Mont,Moisés Rodríguez-Mañero, Andrea Sarkozy, José Luis Merino,David Vivas,Tomás Datino,David Calvo,Nicasio Pérez-Castellano,
Revista Española de Cardiología (2024)
Lilian Gutierrez, Francisco M. Cruz,Alvaro Macias, Ana Isabel Moreno Manuel,Patricia Sanchez-Perez, Maria Linarejos Vera-Pedrosa, Fernando Martínez de Benito, Aitor Díaz-Agustín, Francisco J. Bermúdez-Jiménez, Juan Manuel Ruiz Robles,Isabel Martínez-Carrascoso, Mercedes Martín-Martínez,
Heart Rhythmno. 5 (2024): S323-S324
CARDIOVASCULAR RESEARCH (2024)
Heart rhythmno. 5 (2024): 630-646
NATURE CARDIOVASCULAR RESEARCHno. 12 (2023): 1204-+
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Ana Isabel Moreno Manuel,Alvaro Macias,Francisco M. Cruz,Patricia Sánchez Pérez,Lilian Gutierrez, Isabel M. Carrascoso, María L. Vera Pedrosa,Francisco J. Bermúdez-Jiménez,Jose Jalife
Heart Rhythmno. 5 (2023): S54
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